4833-24-3

Basic information

• Product Name: 2-ETHYL-PYRIDINE 1-OXIDE
• Synonyms: 2-ETHYL-PYRIDINE 1-OXIDE;2-ETHYLPYRIDINE N-OXIDE;2-ethyl-1-oxidanidyl-pyridin-1-ium;2-ethyl-1-oxido-pyridin-1-ium;2-ethyl-1-oxidopyridin-1-ium
• CAS NO: 4833-24-3
• Molecular Formula: C₇H₉NO
• Molecular Weight: 123.15
• EINECS: 225-413-5
• Mol File: 4833-24-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 283.1°C at 760 mmHg
• Flash Point: 125°C
• Appearance: /
• Density: 0.99g/cm³
• Vapor Pressure: 0.00552mmHg at 25°C
• Refractive Index: 1.508
• PKA: pK1:-1.19(+1) (25°C)
• CAS DataBase Reference: 2-ETHYL-PYRIDINE 1-OXIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ETHYL-PYRIDINE 1-OXIDE(4833-24-3)
• EPA Substance Registry System: 2-ETHYL-PYRIDINE 1-OXIDE(4833-24-3)

Safety Data

• Hazardous Substances Data: 4833-24-3(Hazardous Substances Data)

Usage

General Description

2-Ethyl-pyridine 1-oxide is a chemical compound that belongs to the class of pyridines. It is a colorless to light yellow liquid that is primarily used as an intermediate for the synthesis of agrochemicals, pharmaceuticals, and other organic compounds. Its chemical structure consists of a pyridine ring with an ethyl group and an oxygen atom attached to it. It is known for its relatively high stability and can be used as a reagent in various organic reactions. Additionally, it is used as a solvent and can also be found in some industrial and consumer products.

InChI:InChI=1/C7H9NO/c1-2-7-5-3-4-6-8(7)9/h3-6H,2H2,1H3

Upstream product

• 100-71-0 2-Ethylpyridine 

Downstream Products

• 59146-66-6 6-ethyl-2-cyanopyridine 
• 1450659-63-8 4-methylbenzenesulfonate 1-(pyridin-2-yl)ethyl ester 
• 330460-79-2 1-(pyridin-2-yl)ethyl benzoate 
• 1383443-62-6 C₄₀H₄₈N₆O₄ 
• 1260435-67-3 (1R)-1-(2-pyridinyl)ethyl (2S)-3,3,3-trifluoro-2-(methyloxy)-2-phenylpropanoate 
• 1260435-64-0 (1S)-1-(2-pyridinyl)ethyl (2S)-3,3,3-trifluoro-2-(methyloxy)-2-phenylpropanoate 
• 1015759-01-9 C₁₄H₁₅NO 
• 536-33-4 ethionamide 
• 1531-18-6 2-ethyl-4-pyridinecarbonitrile 
• 50826-64-7 4-amino-2-ethylpyridine 
• 3678-65-7 4-chloro-2-ethylpyridine 
• 98420-89-4 4-chloro-2-vinylpyridine 
• 151732-33-1 4-dimethylamino-2-vinylpyridine 
• 121638-26-4 (+/-)-4-chloro-2-(1-hydroxyethyl)pyridine 

Relevant articles and documents

Enantioselective Ni-Catalyzed Electrochemical Synthesis of Biaryl Atropisomers

A scalable enantioselective nickel-catalyzed electrochemical reductive homocoupling of aryl bromides has been developed, affording enantioenriched axially chiral biaryls in good yield under mild conditions using electricity as a reductant in an undivided cell. Common metal reductants such as Mn or Zn powder resulted in significantly lower yields in the absence of electric current under otherwise identical conditions, underscoring the enhanced reactivity provided by the combination of transition metal catalysis and electrochemistry.

Strategic Approach on N-Oxides in Gold Catalysis – A Case Study

An extensive kinetic study of selected key reactions of (oxidative) gold catalysis concentrates on the decrease of the catalytic activity due to inhibition of the gold(I) catalyst caused by pyridine derivatives that are obtained as by-products if N-oxides are applied as oxygen donors. The choice of the examined pyridine derivatives and their corresponding N-oxides has been made regardless of their commercial availability; particular attention has been paid to the practical benefit which up to now has been neglected in most of the reaction screenings. The test reactions were monitored by GC and 1H NMR spectroscopy. The received reaction constants provide information concerning a correlation between the electronic structure of the heterocycle and the catalytic activity. Based on the collected kinetic data, it was possible to develop a basic set of three N-oxides which have to be taken into account in further oxidative gold(I)-catalyzed reactions. (Figure presented.).

3-OXO-TETRAHYDRO-FURO[3,2-B]PYRROL-4(5H)-YL) DERIVATIVES II

The invention relates to amidic oxotetrahydro-2H-furo[3.2-b]pyrrol-4(5H)-yl) derivatives as dual CatS/K inhibitors exhibiting a pronounced CatK-inhibition, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.