98468-72-5

Upstream product

• 637-59-2 1-Bromo-3-phenylpropane 
• 609-08-5 Diethyl methylmalonate 
• 105-53-3 diethyl malonate 
• 26395-09-5 diethyl 2-(3-phenylpropyl)malonate 
• 74-88-4 methyl iodide 

Downstream Products

• 500878-48-8 methyl(3-phenylpropyl)methane-1,1-dicarboxylic acid 
• 523977-99-3 2,3-dihydro-1,3,5-trimethyl-5-(3-phenylpropyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione 
• 523977-97-1 2,3,4,5-tetrahydro-1,3,5-trimethyl-5-(3-phenylpropyl)-2,6-dithioxo-4(1H)-pyrimidinone 
• 26395-15-3 2-methyl-5-phenyl-valeric acid ethyl ester 
• 88783-50-0 2-<3-Phenyl-propyl>-propionsaeure-anilid 
• 143097-60-3 (±)-2-methyl-5-phenylpentanoic acid 

Relevant academic research and scientific papers

Novel pyridopyprimidinone derivatives which are HM74A agonists

The invention is concerned with novel pyridopyrimidinone derivatives of formula (I): wherein R1 to R8, X, Y, m and n are as defined in the description and in the claims. The compounds of the present invention are HM74A agonists with

Intramolecular photoreaction of thiobarbiturates with an alkenyl or a benzyl group in their N-alkyl side chain. Regioselective synthesis of ring-fused pyrimidine derivatives through photocyclization of mono- and dithiobarbiturates

Upon irradiation, thiobarbiturates with an alkenyl (4,5) or a benzyl (14,15,21) group in their N-alkyl side chain give bi- and tri-cyclic fused pyrimidine derivatives through regioselective [2+2] photocycloaddition or Norrish type II reaction, respectively.

Amidocarboxylic acid derivatives

Amidocarboxylic acid derivatives of the formula: wherein R1 represents a hydrogen atom, etc.; R2 represents an alkylene group; R3 represents a hydrogen atom, etc.; R4 represents a hydrogen atom, etc.; X represents a substituted or unsubstituted aryl group, etc.,; Y represents an oxygen atom, etc.; Z represents an alkylene group, etc.; and W represents an alkyl group, etc.; and pharmacologically acceptable salts thereof and pharmacologically acceptable esters thereof are useful as the active ingredient of pharmaceutical compositions. They may be used to treat specified diseases, including diabetes mellitus, hyperlipemia, arteriosclerosis, hypertension, etc.