98476-13-2

Usage

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 25, p. 955, 1988 DOI: 10.1002/jhet.5570250348

Upstream product

• 15001-10-2 ethyl 5-amino-1-(m-tolyl)-1H-pyrazole-4-carboxylate 
• 117378-01-5 1-(3-methylphenyl)-5-(methylthio)-1H-pyrazole-4-carboxylic acid ethyl ester 
• 143-33-9 sodium cyanide 
• 117378-04-8 1-(3-methylphenyl)-5-(methylsulfonyl)-1H-pyrazole-4-carboxylic acid ethyl ester 

Downstream Products

• 103053-17-4 4-carboxy-1-(3-methylphenyl)-5-pyrazolecarboxamide 

Relevant academic research and scientific papers

A New Synthesis of 1-Aryl-5-cyano-1H-pyrazole-4-carboxylic Acid, Ethyl Esters

A novel conversion of 5-amino-1-aryl-1H-pyrazole-4-carboxylic acid, ethyl esters to the corresponding 5-cyano esters is described.The process involves nonaqueous diazotation of the amine to form the methyl thioether, which is oxidized to the methyl sulfon

Cyanopyrazole intermediates

5-Cyano-1-substituted-1H-pyrazole-4-carboxylic acids and esters useful as intermediates to the corresponding 4-carboxyamide derivatives having herbicidal and algicidal activity.