98506-80-0

Basic information

• Product Name: Benzene, 1,1'-[fluoro(phenylsulfonyl)ethenylidene]bis-
• CAS NO: 98506-80-0
• Molecular Formula: C20H15FO2S
• Molecular Weight: 338.402
• Mol File: 98506-80-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-[fluoro(phenylsulfonyl)ethenylidene]bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-[fluoro(phenylsulfonyl)ethenylidene]bis-(98506-80-0)
• EPA Substance Registry System: Benzene, 1,1'-[fluoro(phenylsulfonyl)ethenylidene]bis-(98506-80-0)

Safety Data

• Hazardous Substances Data: 98506-80-0(Hazardous Substances Data)

Upstream product

• 60839-94-3 2-fluoro-methylthiobenzene 
• 119-61-9 benzophenone 
• 20808-12-2 fluoromethyl phenyl sulfone 
• 680624-39-9 tert-butyldimethylsilyl-fluoro-methyl phenyl sulfone 
• 135789-87-6 phosphonic acid diethyl ester 
• 98514-82-0 2-Benzenesulfonyl-2-fluoro-1,1-diphenyl-ethanol 

Downstream Products

• 390-75-0 2-fluoro-1,1-diphenylethene 

Relevant articles and documents

A new synthesis of α-fluorovinylsulfones utilizing the Peterson olefination methodology

α-Fluoro-α-silyl-substituted sulfones 1 are readily prepared from fluoromethyl phenyl sulfone and the appropriate silyl chloride. The use of TBSCl improves both the stability and yield of 1. Lithium derivatives 4 undergo a smooth Peterson olefination reaction with less-enolizable carbonyl compounds to give moderate to good yields of the expected α-fluorovinylsulfones 6, in some cases with high E-stereoselectivity. One-pot reaction with 4 generated in situ from fluoromethyl phenyl sulfone in tetrahydrofuran (THF) also proceeds smoothly, particularly with aldehydes.

A new route to vinyl fluorides

The carbanion of diethyl 1-fluoro-1-(phenylsulfonyl)methanephosphonate (7), generated in situ from fluoromethyl phenyl sulfone (3) undergoes the Horner-Wittig reaction with aldehydes and ketones to yield α-fluoro-α,β-unsaturated sulfones (8). Reductive re