98510-71-5 Usage
Uses
Used in Pharmaceutical Industry:
P-NITROBENZYL-6,6-DIBROMOPENICILLINATE is used as a potential antibiotic for inhibiting the growth of certain bacteria, showcasing its effectiveness in combating bacterial infections.
Used in Drug Delivery Systems:
P-NITROBENZYL-6,6-DIBROMOPENICILLINATE is utilized in the development of drug delivery systems to improve the administration and efficacy of the antibiotic, ensuring targeted delivery and optimized therapeutic outcomes.
Used in Research:
P-NITROBENZYL-6,6-DIBROMOPENICILLINATE serves as a valuable tool for studying penicillin-binding proteins, contributing to a deeper understanding of the mechanisms of action and resistance associated with penicillin-based antibiotics.
Check Digit Verification of cas no
The CAS Registry Mumber 98510-71-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,5,1 and 0 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 98510-71:
(7*9)+(6*8)+(5*5)+(4*1)+(3*0)+(2*7)+(1*1)=155
155 % 10 = 5
So 98510-71-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H14Br2N2O5S/c1-14(2)10(18-12(21)15(16,17)13(18)25-14)11(20)24-7-8-3-5-9(6-4-8)19(22)23/h3-6,10,13H,7H2,1-2H3
98510-71-5Relevant academic research and scientific papers
Synthesis and biological evaluation of penem inhibitors of bacterial signal peptidase
Harris, David A.,Powers, Michael E.,Romesberg, Floyd E.
scheme or table, p. 3787 - 3790 (2010/03/25)
We report the first synthesis of a 5S penem, known to bind bacterial type I signal peptidase, from the commercially available and inexpensive 6-aminopenicillanic acid. We report the first in vivo activity of the compound and use structure-activity relationship studies to begin to define the determinants of signal peptidase binding and also to begin to optimize the penem as an antibiotic.
Design, synthesis, and evaluation of a potent mechanism-based inhibitor for the TEM β-lactamase with implications for the enzyme mechanism
Miyashita, Kazuyuki,Massova, Irina,Taibi, Pascale,Mobashery, Shahriar
, p. 11055 - 11059 (2007/10/02)
The design, synthesis, and evaluation of 6α-(hydroxymethyl)penicillanic acid (4) as a new mechanism-based inhibitor for the class A TEM-1 β-lactamase is described. The design of this compound was aided by computer modeling, using the high-resolution cryst
