98534-82-8

Basic information

• Product Name: 1-(3-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID
• Synonyms: 1-(3-Chlorophenyl)-5-trifluoromethyl-1H-pyrazole-4-carboxylicacid
• CAS NO: 98534-82-8
• Molecular Formula: C₁₁H₆ClF₃N₂O₂
• Molecular Weight: 290.63
• Mol File: 98534-82-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 153～155℃
• Boiling Point: 405°C at 760 mmHg
• Flash Point: 198.7°C
• Appearance: /
• Density: 1.56g/cm³
• Vapor Pressure: 2.76E-07mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(3-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID(98534-82-8)
• EPA Substance Registry System: 1-(3-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID(98534-82-8)

Safety Data

• Hazardous Substances Data: 98534-82-8(Hazardous Substances Data)

Usage

General Description

1-(3-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid is a chemical compound with potential applications in the pharmaceutical industry. It is a pyrazole derivative, containing a chlorophenyl group and a trifluoromethyl group, as well as a carboxylic acid functional group. 1-(3-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID may have a variety of biological activities and therapeutic potential, and could serve as a building block for the synthesis of various drug candidates. Its unique structure and functional groups make it a valuable target for further research and development in the field of medicinal chemistry.

InChI:InChI=1/C11H6ClF3N2O2/c12-6-2-1-3-7(4-6)17-9(11(13,14)15)8(5-16-17)10(18)19/h1-5H,(H,18,19)

Upstream product

• 112055-35-3 1-(3-Chloro-phenyl)-5-trifluoromethyl-1H-pyrazole-4-carboxylic acid ethyl ester 
• 2312-23-4 m-chlorophenylhydrazine hydrochloride 
• 14763-20-3 3-chlorophenyl hydrazine 

Relevant articles and documents

Synthesis, Biological Evaluation, and 3D-QSAR Studies of N-(Substituted pyridine-4-yl)-1-(substituted phenyl)-5-trifluoromethyl-1 H-pyrazole-4-carboxamide Derivatives as Potential Succinate Dehydrogenase Inhibitors

A series of new fungicides that can inhibit the succinate dehydrogenase (SDH) was classified and named as SDH inhibitors by the Fungicide Resistance Action Committee in 2009. To develop more potential SDH inhibitors, we designed and synthesized a novel se

Pyrazole-amides and sulfonamides as sodium channel modulators

Compounds of the present invention modulate PN3 in mammals and are useful in treating pain in mammals.