98534-84-0Relevant academic research and scientific papers
Synthesis, Biological Evaluation, and 3D-QSAR Studies of N-(Substituted pyridine-4-yl)-1-(substituted phenyl)-5-trifluoromethyl-1 H-pyrazole-4-carboxamide Derivatives as Potential Succinate Dehydrogenase Inhibitors
Wu, Zhibing,Park, Hyung-Yeon,Xie, Dewen,Yang, Jingxin,Hou, Shuaitao,Shahzad, Nasir,Kim, Chan Kyung,Yang, Song
, p. 1214 - 1223 (2021/02/06)
A series of new fungicides that can inhibit the succinate dehydrogenase (SDH) was classified and named as SDH inhibitors by the Fungicide Resistance Action Committee in 2009. To develop more potential SDH inhibitors, we designed and synthesized a novel se
SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONISTS
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Page/Page column 158, (2011/02/24)
Disclosed are compounds of Formula (I), or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein: A is formula (II) Q is a substituted 5-membered monocyclic heteroaryl group; W is CH2, O, or NH; and R1, R2, R3, R4, R5, R6, m, n, t, and x are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
Pyrazole-amides and sulfonamides as sodium channel modulators
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Page/Page column 13, (2010/02/10)
Compounds of the present invention modulate PN3 in mammals and are useful in treating pain in mammals.
Pyrazole-amides and sulfonamides as sodium channel modulators
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Page 14, (2010/02/09)
Compounds of the present invention modulate PN3 in mammals and are useful in treating pain in mammals.
