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Upstream product

• 41420-57-9 C₁₇H₁₄O₂ 
• 118-93-4 o-hydroxyacetophenone 
• 104-55-2 3-phenyl-propenal 
• 41420-57-9 (2E,4E)-1-(2-hydroxyphenyl)-5-phenylpenta-2,4-dien-1-one 

Relevant academic research and scientific papers

Glycolytic inhibition and antidiabetic activity on synthesized flavanone scaffolds with computer aided drug designing tools

Background: Diabetes mellitus is a challengeable metabolic disorder that leads to a group of complications when the HbA1c level is not maintained. Most of the existing drugs avail-able in the market in long-term use may lead to serious adverse effects. He

Photochemical Cyclization of 2'-Hydroxychalcones

A series of 4-substituted 2'-hydroxychalcones underwent photocyclization to give the corresponding flavones selectively, but in low quantum yields, on visible irradiation in polar aprotic solvents.Hydroxylic solvents, which disturbed the formation of a cyclic intramolecular hydrogen bond, strongly retarded the photoreaction, while neither triplet quenchers nor free radical inhibitors affected the reaction.The quantum yields were independent of the light intensity, implying a one-photon process, but strongly depended on the wavelength of irradiation.Mechanisms were proposed assuming ?, ?* excited states and Weller's postulate of a dynamic equilibrium in a proton-transfer double-minimum potential.