98603-09-9Relevant academic research and scientific papers
Hydration of terminal alkynes catalyzed by water-soluble cobalt porphyrin complexes
Tachinami, Tadashi,Nishimura, Takuho,Ushimaru, Richiro,Noyori, Ryoji,Naka, Hiroshi
supporting information, p. 50 - 53 (2013/02/23)
Water-soluble cobalt(III) porphyrin complexes were found to promote the hydration of terminal alkynes to give methyl ketones. The alkyne hydration proceeded in good to excellent yield with 0.1 to 2 mol % cobalt catalyst 1 and was compatible with the presence of acid/base- or redox-sensitive functional groups such as alkyl silyl ethers; allyl ethers; trityl ethers; benzyl ethers; carboxylic esters; boronic esters; carboxamides; nitriles; and nitro, iodo, and acetal groups. Some of the alkyne substrates tested here are otherwise difficult to hydrate. The alkyne hydration can be performed on a gram scale, and the catalyst can be recovered by aqueous workup.
Pyridinium Fluorochromate or benzyltrimethylammonium Chlorochromate for selective Oxidation of Alcohols.
Nonaka, Tsuyoshi,Kanemoto, Shigekazu,Oshima, Koichiro,Nozaki, Hitosi
, p. 2019 - 2020 (2007/10/02)
Selective oxidation of secondary alcohols in the presence of primary ones has been achieved by the following sequences, (1) selective protection of primary alcohols with t-BuMe2SiCl, (2) oxidation of secondary alcohols with title reagents, and (3) deprotection of primary hydroxyls.
