98618-78-1

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(3-chloro-2-pyrazinyl)-1-propanone is used as an intermediate in the synthesis of pharmaceuticals for [application reason]. Its unique chemical structure allows for the creation of complex molecules that can be utilized in the development of new drugs.
Used in Agrochemical Production:
In the agrochemical industry, 1-(3-chloro-2-pyrazinyl)-1-propanone is used as a building block for the production of various agrochemicals, such as pesticides and fertilizers, due to its ability to form more complex molecules that can enhance the effectiveness of these products.
Used in Organic Synthesis:
1-(3-chloro-2-pyrazinyl)-1-propanone serves as a key component in organic synthesis, where it is used to create a wide range of complex organic compounds for various applications, including the development of new materials and chemicals.
It is crucial to handle and use 1-(3-chloro-2-pyrazinyl)-1-propanone with care, adhering to proper safety protocols to minimize potential hazards.

Upstream product

• 14508-49-7 2-chloropyrazin 
• 123-38-6 propionaldehyde 
• 1371592-23-2 2-chloro-3-(1-ethoxyprop-1-enyl)pyrazine 

Downstream Products

• 1371592-14-1 1-(3-(1-benzyl-4-chloroindol-3-yl)pyrazin-2-yl)propan-1-one 

Relevant academic research and scientific papers

Synthesis of tetracyclic indoles via intramolecular α-arylation of ketones

Figure Persented: An intramolecular palladium(0)-mediated α-arylation of ketones applied to the synthesis of various substituted tetracyclic indoles is reported. Most significantly, the efficiency of the transformation was enhanced by the use of monoligated Pd(0) complexes. This methodology was extended to double α-arylation of ketones using one-pot reactions with either simultaneous addition or sequential addition of two aryl halides for producing aryl substituted tetracyclic indoles.

Substituent-Directing Effects in the Homolytic Acylation of Pyrazine Derivatives

The homolytic acylation of various monosubstituted pyrazines was studied for a wide spectrum of substituents.Methoxy and chloro substituents were found to direct ortho substitution, thus giving the corresponding 2,3-disubstituted pyrazines.Acetyl, carbethoxy, and carboxamide groups were found to direct para substitution, thus leading to the corresponding 2,5-disubstituted pyrazines.These selectivities result from the combination of the inductive and resonance effects of the substituents.The synthetic potential of the acylation reaction is demonstrated in the preparation of some novel pyrazine flavorants.

Smoking compositions containing acylpyrazine ether flavorants

In one of its embodiments the present invention provides a smoking composition which contains a novel type of acylpyrazine ether flavorant additive as exemplified by 1-(3-methoxy-2-pyrazinyl)-2-methyl-1-propanone. STR1