Welcome to LookChem.com Sign In|Join Free
  • or
Sobuzoxane is a novel bis(2,6-dioxopiperazine) derivative that exhibits a broad spectrum of antitumor activity. It is a noncleavable complex-stabilizing topoisomerase II inhibitor that interferes with the catalytic activity of the enzyme, resulting in an irreversible inhibition of cell division by blockade of chromosome condensation and segregation. Due to its unique mode of cytocidal activity, it has no cross resistance with many currently available anticancer agents. Sobuzoxane is reported to significantly inhibit the growth of human colon, lung, gastric, and breast cancers and is in clinical trials for these indications.

98631-95-9

Post Buying Request

98631-95-9 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

98631-95-9 Usage

Uses

Used in Oncology:
Sobuzoxane is used as an antitumor agent for the treatment of malignant lymphoma and adult T-cell leukemia-lymphoma (ATLL), which is resistant to chemotherapy and has a poor prognosis. It is also in clinical trials for the treatment of human colon, lung, gastric, and breast cancers.
Sobuzoxane is used as an inhibitor of DNA topoisomerase II, which induces apoptosis.

Originator

Zenyaku Kogyo (Japan)

Check Digit Verification of cas no

The CAS Registry Mumber 98631-95-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,6,3 and 1 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 98631-95:
(7*9)+(6*8)+(5*6)+(4*3)+(3*1)+(2*9)+(1*5)=179
179 % 10 = 9
So 98631-95-9 is a valid CAS Registry Number.
InChI:InChI=1/C22H34N4O10/c1-15(2)11-33-21(31)35-13-25-17(27)7-23(8-18(25)28)5-6-24-9-19(29)26(20(30)10-24)14-36-22(32)34-12-16(3)4/h15-16H,5-14H2,1-4H3

98631-95-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name [4-[2-[4-(2-methylpropoxycarbonyloxymethyl)-3,5-dioxopiperazin-1-yl]ethyl]-2,6-dioxopiperazin-1-yl]methyl 2-methylpropyl carbonate

1.2 Other means of identification

Product number -
Other names MST-16

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:98631-95-9 SDS

98631-95-9Downstream Products

98631-95-9Relevant academic research and scientific papers

Bis-dioxopiperazine derivatives, process for their preparation, antitumor agents comprising them and compositions containing them

-

, (2008/06/13)

Disclosed are novel bis-dioxopiperazine derivatives and non-toxic salts thereof, process for their preparation, antitumor agents comprising them and compositions containing them. The bis-dioxopiperazine derivatives are represented by the following general

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 98631-95-9