98684-32-3

Usage

General Description

2-(2-Methoxyethoxy)benzoic acid is a chemical compound with the molecular formula C11H14O5. It is also known as MEBP and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2-(2-METHOXYETHOXY)BENZOIC ACID is a white crystalline solid that is insoluble in water but soluble in organic solvents. It is used as a building block in the manufacture of various products, including dyes, fragrances, and polymers. Additionally, 2-(2-Methoxyethoxy)benzoic acid has been studied for its potential antiproliferative and anti-inflammatory properties. However, it is important to handle 2-(2-METHOXYETHOXY)BENZOIC ACID with caution, following strict safety protocols, as it may be harmful if ingested or inhaled.

Upstream product

• 6482-24-2 2-Bromoethyl methyl ether 
• 119-36-8 methyl salicylate 
• 108-95-2 phenol 
• 143767-40-2 methyl 2-(2-methoxyethoxy)benzoate 

Downstream Products

• 80144-02-1 2-(2-methoxyethoxy)benzoyl chloride 

Relevant academic research and scientific papers

COLORED CURABLE COMPOSITION, COLORED CURED FILM, COLOR FILTER AND PRODUCTION METHOD THEREOF, DISPLAY APPARATUS, SOLID-STATE IMAGING DEVICE, AND COMPOUND

A colored curable composition is provided, which has excellent storage stability and can be used to obtain a colored cured film and a color filter having excellent heat resistance, brightness, contrast and pattern shapes. The colored curable composition contains: a polymerizable compound, and at least one selected from groups consisting of a compound represented by the following general formula (I) and a tautomer thereof. General Formula (I)

An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors

Sphingosine kinase 1 (SphK1), the enzyme that produces the bioactive sphingolipid metabolite, sphingosine-1-phosphate, is a promising new molecular target for therapeutic intervention in cancer and inflammatory diseases. In view of its importance, the main objective of this work was to find new and more potent inhibitors for this enzyme possessing different structural scaffolds than those of the known inhibitors. Our theoretical and experimental study has allowed us to identify two new structural scaffolds (three new compounds), which could be used as starting structures for the design and then the development of new inhibitors of SphK1. Our study was carried out in different steps: virtual screening, synthesis, bioassays and molecular modelling. From our results, we propose a new dihydrobenzo[b]pyrimido[5,4-f]azepine and two alkyl{3-/4-[1-hydroxy-2-(4-arylpiperazin-1-yl)ethyl]phenyl}carbamates as initial structures for the development of new inhibitors. In addition, our molecular modelling study using QTAIM calculations, allowed us to describe in detail the molecular interactions that stabilize the different Ligand-Receptor complexes. Such analyses indicate that the cationic head of the different compounds must be refined in order to obtain an increase in the binding affinity of these ligands.

BENZODIAZEPINE DERIVATIVES FOR TREATING HEPATITIS C INFECTION

The invention concerns benzodiazepine derivatives of Formula (I) wherein W, X, L1, L2, L3, R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment or prophylaxis of hepatitis C virus infection.

NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF

The present invention relates to compounds of formula (I), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, formula (I). wherein R1, R2, R3, R4, and L1 are defined in the specfication, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. The present invention also relates to compounds of formula (II), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, formula (II). wherein R1a, R2a, Rx, and n are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.

NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF

The present invention relates to compounds of formula (I), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, and L1 are defined in the specfication, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. The present invention also relates to compounds of formula (II), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1a, R2a and (Rx)n are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.

Pyrazolopyrimidinones which inhibit type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterase (cGMP PDE5) for the treatment of sexual dysfunction

Compounds of formulae (IA) and (IB) or pharmaceutically or veterinarily acceptable salts thereof, or pharmaceutically or veterinarily acceptable solvates of either entity, wherein R1 is C1 to C3 alkyl substituted with C3 to C6 cycloalkyl, CONR5R6 or a N-linked heterocyclic group; (CH2)nHet or (CH2)nAr; R2 is C1 to C6 alkyl; R3 is C1 to C6 alkyl optionally substituted with C1 to C4 alkoxy; R4 is SO2NR7R8; R5 and R6 are each independently selected from H and C1 to C4 alkyl optionally substituted with C1 to C4 alkoxy, or, together with the nitrogen atom to which they are attached, form a 5- or 6-membered heterocyclic group; R7 and R8, together with the nitrogen atom to which they are attached, form a 4-R10-piperazinyl group; R10 is H or C1 to C4 alkyl optionally substituted with OH, C1 to C4 alkoxy or CONH2; H is an optionally substituted C-linked 5- or 6-membered heterocyclic group; Ar is optionally substituted phenyl; and n is 0 or 1; are potent and selective cGMP PDE5 inhibitors useful in the treatment of, inter alia, male erectile dysfunction and female sexual dysfunction.

ortho-Directed Lithiation of (2-Methoxy)ethoxy- and (2-Dimethylamino)ethoxy-arenes

ortho-Directed lithiation of a number of (2-methoxy)ethoxy- and (2-dimethylamino)ethoxy-arenes has been investigated.Lithiation of these compounds followed by treatment with various electrophiles afforded ortho-substituted products in moderate to excellent yields.Keywords-ortho-directed lithiation; (2-methoxy)ethoxyarene; (2-dimethylamino)ethoxyarene; regioselectivity