98689-10-2

Upstream product

• 98689-09-9 9-Hydroxy-9-(2-methoxy-phenoxymethyl)-2,12-dioxo-3-oxa-6-aza-tricyclo[6.3.1.0^1,5]dodecane-6-carboxylic acid benzyl ester 
• 98689-05-5 methyl 1,4,5,6-tetrahydro-2-(acetoxymethyl)-1-<(benzyloxy)carbonyl>-4-oxo-3-pyridinecarboxylate 
• 98689-08-8 3-hydroxy-4-(2-methoxyphenoxy)but-1-ene 
• 93758-01-1 (2-methoxyphenoxy)methyl vinyl ketone 
• 68185-61-5 methyl 1,4,5,6-tetrahydro-2-methyl-4-oxo-3-pyridinecarboxylate 
• 18167-91-4 2(2-methoxyphenoxy)ethanale 
• 98689-04-4 methyl 1,4,5,6-tetrahydro-1-<(benzyloxy)carbonyl>-2-(bromomethyl)-4-oxo-3-pyridinecarboxylate 
• 98689-07-7 1-<(benzyloxy)carbonyl>-2-(hydroxymethyl)-4-oxo-3-piperidinecarboxylic acid γ-lactone 
• 98689-06-6 1,4,5,6-tetrahydro-1-<(benzyloxy)carbonyl>-2-(hydroxymethyl)-4-oxo-3-pyridinecarboxylic acid γ-lactone 
• 98689-03-3 methyl 1,4,5,6-tetrahydro-1-<(benzyloxy)carbonyl>-2-methyl-4-oxo-3-pyridinecarboxylate 

Downstream Products

• 98689-12-4 6a-Hydroxy-7-(2-methoxy-phenoxy)-octahydro-furo[3,4-j]isoquinoline-1,8-dione 
• 98689-11-3 7-(2-Methoxy-phenoxy)-3a,4,5,6,9,10-hexahydro-3H-furo[3,4-j]isoquinoline-1,8-dione 

Relevant academic research and scientific papers

Studies Directed at a Synthesis of Morphine Alkaloids. Regiocontrol in Robinson-Type Annelation of 2-(Hydroxymethyl)-4-oxo-3-piperidinecarboxylic Acid γ-Lactones

Conjugate reduction of 5a with NaBH4 in THF-pyridine, followed by sequential addition of excess benzaldehyde and ethanolic hydrochloric acid, gives keto lactone 6a, uncontaminated with lactonic alcohol 7a.Annelation of 6a with (2-methoxyphenoxy)methyl vin