98754-28-0

Usage

Chemical structure

1-Benzyl-N-[(2-nitrophenyl)methyl]piperidin-4-amine is a complex chemical compound with a benzyl group, a nitrophenylmethyl group, and a piperidin-4-amine group.

Potential applications

It has potential applications in the field of medicinal chemistry and drug development.

Pharmacological activities

Piperidine derivatives, like 1-Benzyl-N-[(2-nitrophenyl)-methyl]piperidin-4-amine, have been studied for their pharmacological activities, including as analgesics and anesthetics.

Nitro group addition

The addition of a nitro group to the phenylmethyl moiety may impart certain chemical and biological properties to the compound.

Further research

Further research is likely needed to fully understand the potential uses and effects of 1-Benzyl-N-[(2-nitrophenyl)-methyl]piperidin-4-amine.

Upstream product

• 16940-66-2 sodium tetrahydroborate 
• 50541-93-0 4-amino-1-benzylpiperidine 
• 552-89-6 2-nitro-benzaldehyde 

Downstream Products

• 79098-75-2 3-piperidin-4-yl-3,4-dihydro-1H-quinazoline-2-one 
• 1443256-63-0 3-(1-benzyl-piperidin-4-yl)-1-methyl-3,4-dihydro-1H-quinazolin-2-one 
• 79098-88-7 1-benzyl-4-(1,2,3,4-tetrahydro-2-oxo-3-quinazolinyl)piperidine 
• 337909-92-9 4-Amino-3-[(1-benzyl-piperidin-4-yl-amino)-methyl]-phenol 
• 79099-03-9 2-amino-N-[1-(phenylmethyl)-4-piperidinyl]-benzenemethanamine 

Relevant academic research and scientific papers

NOVEL COMPOUNDS

This invention relates to compounds of formula I their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, X, R1, R2, R3 have meanings given in the description.

1,2,4 -TRIAZOLES AS ALLOSTERIC MODULATORS OF MGLU5 RECEPTOR ACTIVITY FOR THE TREATMENT OF SCHIZOPHRENIA OF DEMENTIA

This invention relates to compounds of formula (I) their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, X, R1, R2, R3 have meanings given in the description.

DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS

Autophagy inducing compounds, methods of their preparation and use, and kits containg said compounds are disclosed herein.

Process for preparing 1- [N2-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazine

The present application relates to a process for preparing the CGRP-antagonist 1-[N2-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazine of formula by means of which this compound can be prepared in large amounts, in high yields and with high purity.