98786-42-6Relevant academic research and scientific papers
Synthesis of 2,6-Diaryl-4H-thiopyran-4-ones
Boaz, Neil W.,Fox, Kristine M.
, p. 3042 - 3045 (2007/10/02)
A novel synthesis of 2,6-diaryl-4H-thiopyran-4-ones has been developed.The title compounds were prepared by two sequential thio-Claisen condensations of a dialkyl ketone and two dithioesters.The intermediate β-thioxo ketone from the first condensation was converted to the corresponding β-(methylthio)enone for both protection and reactivity purposes.Facile addition-elimination of the methylthio moiety by a β-thioxo ketone enolate generated in the second thio-Claisen condensation afforded the desired heterocycle.This new method is rapid and simple with the only requirement being moderate substituent alkaline stability.
THE OXIDATION REACTIONS OF THIOPYRANS
Plotnikov, A. M.,Shebaldova, A. D.,Kharchenko, V. G.
, p. 1226 - 1229 (2007/10/02)
A method was developed for the preparation of compounds with 4H-thiopyrone structure by the oxidation of the corresponding 4H-thiopyranes and their condensed analogs by potassium permanganate.
