98816-61-6

Basic information

• Product Name: 4-BROMO-N,N-DIISOPROPYLBENZYLAMINE, 95
• Synonyms: 4-BROMO-N,N-DIISOPROPYLBENZYLAMINE, 95;4-Bromo-N,N-diisopropylbenzenemethanamine;N-(4-Bromobenzyl)-N-isopropylpropan-2-amine;[(4-bromophenyl)methyl]bis(propan-2-yl))amine;N-(4-bromobenzyl)-N,N-diisopropylamine
• CAS NO: 98816-61-6
• Molecular Formula: C₁₃H₂₀BrN
• Molecular Weight: 270.21505
• Mol File: 98816-61-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 65 °C1 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.157 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0563mmHg at 25°C
• Refractive Index: n20/D 1.524(lit.)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-BROMO-N,N-DIISOPROPYLBENZYLAMINE, 95(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-N,N-DIISOPROPYLBENZYLAMINE, 95(98816-61-6)
• EPA Substance Registry System: 4-BROMO-N,N-DIISOPROPYLBENZYLAMINE, 95(98816-61-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 98816-61-6(Hazardous Substances Data)

Usage

General Description

4-BROMO-N,N-DIISOPROPYLBENZYLAMINE, 95 is a chemical compound that is commonly used as a reagent in organic synthesis. It is a clear, colorless to slightly yellow liquid with a strong, amine-like odor. 4-BROMO-N,N-DIISOPROPYLBENZYLAMINE, 95 is primarily used in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. It is also utilized as an intermediate in the synthesis of various fine chemicals. Its high purity grade of 95% ensures that it is suitable for use in a wide range of applications. This chemical is highly reactive and should be handled with care, following proper safety protocols.

InChI:InChI=1/C13H20BrN/c1-10(2)15(11(3)4)9-12-5-7-13(14)8-6-12/h5-8,10-11H,9H2,1-4H3

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 108-18-9 diisopropylamine 
• 589-15-1 1-bromomethyl-4-bromobenzene 

Downstream Products

• 60376-97-8 N-(4-bromobenzyl)isopropylamine 
• 1394862-51-1 C₃₈H₄₆N₄O₂ 
• 1122-91-4 4-bromo-benzaldehyde 
• 1025900-35-9 4-[(N,N-diisopropylamino)methyl]phenylboronic acid 
• 98816-60-5 4-diisopropylaminomethyltriphenylphosphine 

Relevant articles and documents

Synthesis of tertiary amines by direct Br?nsted acid catalyzed reductive amination

Tertiary amines are ubiquitous and valuable compounds in synthetic chemistry, with a wide range of applications in organocatalysis, organometallic complexes, biological processes and pharmaceutical chemistry. One of the most frequently used pathways to synthesize tertiary amines is the reductive amination reaction of carbonyl compounds. Despite developments of numerous new reductive amination methods in the past few decades, this reaction generally requires non-atom-economic processes with harsh conditions and toxic transition-metal catalysts. Herein, we report simple yet practical protocols using triflic acid as a catalyst to efficiently promote the direct reductive amination reactions of carbonyl compounds on a broad range of substrates. Applications of this new method to generate valuable heterocyclic frameworks and polyamines are also included.

Bronsted base-assisted boronic acid catalysis for the dehydrative intramolecular condensation of dicarboxylic acids

Bronsted base-assisted boronic acid catalysis for the dehydrative self-condensation of carboxylic acids is described. Arylboronic acid bearing bulky (N,N-dialkylamino)methyl groups at the 2,6-positions can catalyze the intramolecular dehydrative condensation of di-and tetracarboxylic acids. This is the first successful method for the catalytic dehydrative self-condensation of carboxylic acids.(Figure Presented)

4-DIISOPROPYPAMINOMETHYLTRIPHENYLPHOSPHINE: A WATER SOLUBLE WITTIG REAGENT

4-Diisopropylaminomethyltriphenylphosphine (1) is trivially prepared, is essentially interchangeable with triphenylphosphine in the Wittig reaction, and can be removed by aqueous acid extraction subsequent to the Wittig reaction, simplifying purification.