98819-63-7

Upstream product

• 134-81-6 benzil 
• 85891-96-9 ((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-acetic acid (1S,2S)-2-[2-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyloxy)-acetoxy]-1,2-diphenyl-ethyl ester 
• 98819-58-0 (+)-1S,2S-(1,2-diphenyl-1,2-ethanedioxy)-diacetic acid 
• 98769-48-3 meso-(1,2-diphenyl-1,2-ethanedioxy)-diacetic acid 
• 655-48-1 DL-1,2-diphenylethane-1,2-diol 
• 579-43-1 (1S,2R)-1,2-diphenylethane-1,2-diol 
• 80158-28-7 (1R*,2S*)-2,2'-(1,2-Diphenylethandiyldioxy)diethanol 
• 98819-61-5 2,2'-(((1S,2S)-1,2-diphenylethane-1,2-diyl)bis(oxy))bis(ethan-1-ol) 
• 98769-47-2 (+/-)-(1,2-diphenyl-1,2-ethanedioxy)-diacetic acid 
• 80158-27-6 (+/-)-2,2'-(1,2-diphenyl-1,2-ethanedioxy)-diethanol 
• 2325-10-2 (S,S)-hydrobenzoin 

Relevant academic research and scientific papers

SYNTHESIS OF (-)-2S,3S,11S,12R-2,3,11,12-TETRAPHENYLCROWN-6

The synthesis of (-) 2S,3S,11S,12R-2,3,11,12-tetraphenyl-crown-6 from (-)-1S,2S-hydrobenzoin and meso-hydrobenzoin is described.Chemical shifts and vicinal coupling constants of the benzylic protons in the 2S,3S and 11S,12R substructures in the free ligands and in complexes with KSCN and 1-phenylethylammonium bromides and a brief discussion of the related conformational changes are also presented.A detailed procedure for the resolution of racemic hydrobenzoin is given.

Enantioselective Reductions of Aromatic Ketones with Ammonia-Borane Complexes of Chiral Tetraphenyl-18-crown-6 Derivatives

Enantioselective reductions of prochiral aromatic ketones with adducts formed between ammonia-borane and (2R,3R,11R,12R)- and (2S,3S,11S,12S)-tetraphenyl-1,4,7,10,13,16-hexaoxacyclo-octadecane, (RRRR)-(3) and (SSSS)-(3), have afforded the corresponding (S) and (R) aromatic secondary alcohols with enantiomeric excesses of 20-67percent.