98832-89-4Relevant academic research and scientific papers
Quinazolinone derivatives: Synthesis and binding evaluation on cholecystokinin receptors
Varnavas,Lassiani,Luxich,Zacchigna,Boccu
, p. 333 - 339 (2007/10/03)
A series of 2-methyl-3-amino-4(H)-quinazolinone and of 2-phenyl-3-amino-4(H)-quinazolinone derivatives were synthesized and examined for their CCK receptor affinities. These compounds displayed micromolar affinities for CCK-B rather than CCK-A receptor and the obtained results confirm that the 4(3H)-quinazolinone nucleous represent a useful template for the development of selective CCK-B receptor ligands.
Synthesis and Pharmacological Activity of Some New 4(3H)-Quinazolone Derivatives
Ossman, Abdel Rahman El Nasser,Safwat, H. M.,Aziza, Mohsen A.
, p. 333 - 335 (2007/10/02)
New derivatives of 2-methyl-4(3H)-quinazolone have been prepared and their structures assigned on the basis of IR, PMR and mass spectra.Some of them show CNS depressant activity.
