98889-63-5Relevant academic research and scientific papers
SYNTHETIC APPROACH TO BACTERIAL LIPOPOLYSACCHARIDE ,PREPARATION OF TRISACCHARIDE PART STRUCTURES CONTAINING KDO AND 1-DEPHOSPHO LIPID A
Imoto, Masahiro,Kusunose, Naoto,Kusumoto, Shoichi,Shiba, Tetsuo
, p. 2227 - 2230 (2007/10/02)
Title compounds (1a,b) and an analogous disaccharide (2a) were synthesized via a reaction of a ketosidic fluoride of 3-deoxy-D-manno-2-octulosonic acid (KDO) (3) with phosphorylated acyl glucosamine di- and monosaccharides.
Total Synthesis of Escherichia coli Lipid A, the Endotoxically Active Principle of Cell-Surface Lipopolysaccharide
Imoto, Masahiro,Yoshimura, Hiroyuki,Shimamoto, Tetsuo,Sakaguchi, Nobuki,Kusumoto, Shoichi,Shiba, Tetsuo
, p. 2205 - 2214 (2007/10/02)
Chemical synthesis are described of polyacylated β(1->6) glucosamine disaccharide 1,4'-bis(phosphate), which corresponds to the proposed structure of E. coli lipid A, and of its dephospho derivatives.The synthetic bisphosphate proved to be identical with
