98919-13-2

Usage

InChI:InChI=1/C9H10Cl2O2/c1-6(5-12)13-9-3-2-7(10)4-8(9)11/h2-4,6,12H,5H2,1H3

Upstream product

• 63650-24-8 2-(4-chlorophenoxy)-1-propanol 
• 4169-04-4 2-phenoxy-1-propanol 
• 120-83-2 2,4-dichlorophenol 
• 120-36-5 2-(2,4-dichlorophenoxy)propionic acid 

Downstream Products

• 97642-92-7 (R)-2-methyl-2-(2,4-dichlorophenoxy)ethanol 
• 87810-53-5 (S)-(+)-2-methyl-2-(2,4-dichlorophenoxy)ethanol 
• 53552-65-1 2-(2,4-dichlorophenoxy)propanal 
• 120-36-5 2-(2,4-dichlorophenoxy)propionic acid 

Relevant academic research and scientific papers

A method for preparing chloro-benzene oxygen carboxylic acid (by machine translation)

The invention provides a method for preparing carboxylic acid chloro-benzene oxygen, comprising the following steps: S1) phenoxy fatty alcohol in the catalyst B A and under the action of the catalyst, and the chlorinating agent to 2 bit and/or 4 bit selective chlorination reaction, to obtain chloro-benzene oxygen fatty alcohol; said catalyst A is Lewis acid; said catalyst B is C5 - 22 of the thioether, thiazole, isothiazole, thiophene or their halogenated derivatives; S2) [...] fatty alcohol and water, under the action of a catalyst, and an oxidizing agent for the selective catalytic oxidation reaction, get chloro-benzene oxygen carboxylic acid. The invention through the re-design of the process route, the catalyst and the chlorinating agent fine screening, effectively reduces the energy consumption, the selectivity of the dichloride to improve at the same time avoiding the losses of the active ingredient, the resulting chloro-benzene oxygen carboxylic acid content can be up to 98.5% or more, the total yield can be up to 99% or more. (by machine translation)

New Synthesis of Known Herbicides Based on Aryloxyalkanoic Acids

A new version has been proposed for the synthesis of analogs of the known herbicides mecoprop (MCPP) and dichlorprop (2,4-DP) by ozonolysis of chloro derivatives of (pent-3-en-2-yloxy)benzene.

Resolution of 2-aryloxy-1-propanols via lipase-catalyzed enantioselective acylation in organic media

2-Aryloxy-1-propanols, primary alcohols with an oxygen atom at the stereocenter, were resolved with good to high enantioselectivity by acylation with vinyl butanoate mediated by Pseudomonas sp. lipase in di-iso-propyl ether. Potential factors affecting the enantioselectivity of the enzymatic acylation were examined: solvents, acyl donors and temperature. Using this enantioselective acylation procedure, enantiomerically pure (R)-2-(4-chlorophenoxy)-1-propanol was prepared on a gram scale.

Pyrimidine derivatives, pharmaceutical compositions and method of using same

Compounds of the formula STR1 wherein A is C1-8 -alkylene, R1 is halogen, C1-4 -alkyl or halo-(C1-4 -alkyl), R2 is hydrogen, hydroxy or acyloxy, R3 is hydrogen or C1-4 -alkyl, R4 is aryl or aryloxy and X is O or NH, and tautomers thereof are described. The compounds of formula I and their tautomers possess antiviral activity and can be used in the form of medicaments for the control and prevention of viral infections.