98927-91-4

Upstream product

• 18403-22-0 (3aS,6S,7R,7aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol 
• 74-88-4 methyl iodide 
• 7473-38-3 benzyl β-L-arabinopyranoside 
• 87-72-9 L-(+)-arabinose 
• 77-78-1 dimethyl sulfate 
• 100-51-6 benzyl alcohol 

Downstream Products

• 98928-06-4 benzyl 4-O-isopropyl-2-O-methyl-β-L-arabinopyranoside 

Relevant academic research and scientific papers

BIARYL AMIDES WITH MODIFIED SUGAR GROUPS FOR TREATMENT OF DISEASES ASSOCIATED WITH HEAT SHOCK PROTEIN PATHWAY

Provided are biaryl amides and coumarin-based compounds with modified sugar groups for treatment of diseases associated with heat shock protein pathway. The compounds having the following formulas, wherein variables are as defined herein. Formulae (I), (II), (III), (IV), and (V), Pharmaceutical compositions of the compounds are also provided. These biaryl amides and coumarin-based derivatives with modified sugar groups are useful for treatment and prevention of diseases and disorders, including neurological disorders, such as neurodegenerative diseases and nerve damaging disorders, for example, diabetic peripheral neuropathy.

SYNTHESIS AND HYDROGENOLYSIS OF THE METHYLENE, ETHYLIDENE, ISOPROPYLIDENE, AND DIASTEREOISOMERIC 1-PHENYLETHYLIDENE ACETALS OF β-L-ARABINO- AND α-L-RHAMNOPYRANOSIDE DERIVATIVES

Both diastereoisomers of 1-phenylethylidene acetals (acetophenone acetals) of methyl and benzyl β-L-arabinopyranoside and α-L-rhamnopyranoside were prepared.Acetal-exchange reactions gave only the endo-phenyl isomers; their 2-O- and 4-O-acetyl derivatives