98961-97-8 Usage
Description
PIPERAZINE-1-SULFONIC ACID DIMETHYLAMIDE is a synthetic chemical compound characterized by its molecular formula C6H14N2O3S. It is recognized for its buffering capabilities, which allow it to maintain a constant pH level in solutions. This property, along with its stability, makes it a valuable component in various industries, including pharmaceuticals, cosmetics, and biochemical research.
Uses
Used in Pharmaceutical Industry:
PIPERAZINE-1-SULFONIC ACID DIMETHYLAMIDE is used as a buffering agent for maintaining the pH of pharmaceutical formulations, ensuring the stability and efficacy of drugs. Its ability to control pH levels is crucial in the production of various medications, contributing to their quality and performance.
Used in Cosmetics Industry:
In the cosmetics industry, PIPERAZINE-1-SULFONIC ACID DIMETHYLAMIDE serves as a buffering agent, helping to maintain the pH balance of cosmetic products. This ensures the stability of the formulations and contributes to their effectiveness and safety for consumer use.
Used in Biochemical Research:
PIPERAZINE-1-SULFONIC ACID DIMETHYLAMIDE is utilized as a reagent in biochemical research, where its buffering properties are essential for conducting experiments under controlled pH conditions. This aids in the accurate study of biological processes and the development of new research methodologies.
Used as a Stabilizer in Medications:
PIPERAZINE-1-SULFONIC ACID DIMETHYLAMIDE is also employed as a stabilizer in certain medications, enhancing their shelf life and maintaining their potency over time. Its stabilizing effect is beneficial in preserving the integrity of pharmaceutical products during storage and distribution.
Check Digit Verification of cas no
The CAS Registry Mumber 98961-97-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,9,6 and 1 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 98961-97:
(7*9)+(6*8)+(5*9)+(4*6)+(3*1)+(2*9)+(1*7)=208
208 % 10 = 8
So 98961-97-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H15N3O2S/c1-8(2)12(10,11)9-5-3-7-4-6-9/h7H,3-6H2,1-2H3
98961-97-8Relevant articles and documents
Synthesis and evaluation of 4-(2-hydroxypropyl)piperazin-1-yl) derivatives as Hsp90 inhibitors
Cherfaoui, Bahidja,Guo, Tian-Kun,Sun, Hao-Peng,Cheng, Wei-Lin,Liu, Fang,Jiang, Fen,Xu, Xiao-Li,You, Qi-Dong
supporting information, p. 2423 - 2432 (2016/05/24)
We previously reported 4-(3-((6-bromonaphthalen-2-yl)oxy)-2-hydroxypropyl)-N,N-dimethylpiperazine-1-sulfonamide (1) as a novel heat shock protein 90 inhibitor with moderate activity. In our ongoing efforts for the discovery of Hsp90 modulators we undertake structural investigations on 1. Series of the titled compound were designed, synthesized and evaluated. We have found that compounds with a hydroxyl group at C-4 of the aryl ring on the piperazine moiety possess Hsp90 inhibition properties. Compound 6f with improved activity could be further developed and optimized as Hsp90 inhibitor.
Multifunctional Compounds and Methods of Use Thereof
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Page/Page column 9, (2009/05/29)
Compositions comprising multifunctional agents and methods of use thereof are provided.
ISOTHIAZOLE DIOXIDES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS
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Page/Page column 266, (2010/02/13)
Disclosed are novel compounds of the formula (IA): and the pharmaceutically acceptable salts and solvates thereof. D and E are different groups wherein one is N and the other is CR50. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, pain (e.g., acute pain, acute and chronic inflammatory pain, and neuropathic pain) using a compound of formula IA.