99030-33-8Relevant academic research and scientific papers
Construction of Five-Membered Rings by Michael Addition-Radical Cyclization
Clive, Derrick L.J.,Boivin, Taryn L.B.,Angoh, A. Gaeetan
, p. 4943 - 4953 (2007/10/02)
Enamines react with Michael acceptors 8-10 to produce ketones that, on treatment with lithium acetylides, afford hydroxy acetylenes 3.These compounds then undergo radical cyclization when treated with triphenyltin hydride and AIBN.The products 6 are forme
2-(Phenylseleno)prop-2-enenitrile: a Three-carbon Unit for Radical Cyclization
Angoh, A. Gaaetan,Clive, Derrick L. J.
, p. 941 - 942 (2007/10/02)
Successive reaction of enamines with 2-(phenylseleno)prop-2-enenitrile, lithium phenylacetylide, and triphenyltin hydride serves to generate carbocycles by a process of radical ring closure.
Radical Annulation: A Method for Preparation of Carbocycles
Angoh, Gaeatan A.,Clive, Derrick L. J.
, p. 980 - 982 (2007/10/02)
β-Acetylenic radicals, e.g., (6b) and (12), generated in three steps from epoxides or in two steps from α-halogenoketones, respectively, react with electron-defficient olefins to produce five-membered carbocycles by a process of conjugate addition and 5-e
