99047-22-0Relevant academic research and scientific papers
1,4-dihydropyridines
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, (2008/06/13)
This invention provides compounds useful for treating coronary insufficiency, hypertension, angina pectoris, cardiac arrythmia, heart attack or coronary vasospasm and represented by the general formula: STR1 R1 and R2 are each independently selected from the group consisting of lower alkyl, N-alkylphthalimido and derivatives of N-alkylphthalimido, wherein said N-alkyl group comprises at least 2 carbon atoms; A is a straight or branched chain hydrocarbon moiety containing from 1 to 12 carbon atoms and from 0 to 2 double bonds; R3 is selected from the group of radicals consisting of hydrogen, --NH2 and --NCS; R4 is an aryl or heteroaryl radical; and R5 is a lower alkyl radical or A--R3 ; provided that when R3 is a hydrogen radical at least one of R1 and R2 is not lower alkyl, including both pure enantiomers as well as mixtures thereof; and pharmaceutically-acceptable salts thereof.
1,4-dihydropyridine derivatives
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, (2008/06/13)
New compounds which act on the cardiac circulation and correspond to the general formula STR1 and may be used for the treatment of cardiac diseases, in certain forms of hypertension and in diseases of arterial occlusion are described. Methods of preparation for these compounds and medicaments containing these compounds are also described.
