99072-47-6Relevant academic research and scientific papers
Hydrolysis of acyloxy nitroso compounds yields nitroxyl (HNO)
Sha, Xin,Isbell, T. Scott,Patel, Rakesh P.,Day, Cynthia S.,King, S. Bruce
, p. 9687 - 9692 (2006)
Nitroxyl (HNO/NO-), the reduced form of nitric oxide, has gained attention based on its separate chemistry and biology from nitric oxide. The inherent reactivity of HNO requires new and mechanistically unique donors for the detailed study of HN
Acylation of Nitronates: [3,3]-Sigmatropic Rearrangement of in Situ Generated N-Acyloxy, N-oxyenamines
Kokuev, Aleksandr O.,Antonova, Yulia A.,Dorokhov, Valentin S.,Golovanov, Ivan S.,Nelyubina, Yulia V.,Tabolin, Andrey A.,Sukhorukov, Alexey Yu.,Ioffe, Sema L.
, p. 11057 - 11066 (2018/09/06)
Acylation of nitronates affords α-acyloxyoxime derivatives via an umpolung functionalization of the α-position. This transformation involves generation of hitherto unknown N-acyloxy,N-oxyenamines and their fast [3,3]-sigmatropic rearrangement driven by the cleavage of the weak N-O bond. The reaction has a broad scope, and it is regioselective in the case of nitronates possessing nonsymmetrically substituted α-positions. Application to the formal total synthesis of clausenamide and cis-clausenamide is presented.
C-NITROSO-DERIVED NITROXYL DONORS
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Page/Page column 17, (2008/06/13)
Active compounds of Formula (I) are described: wherein: R1 and R2 are each independently C1-C4 alkyl; or R1 and R2 together form a C2-C7 alkylene chain; and Z is a non-steroidal anti-inflammatory drug (NSAID); a
Azodioxides activated by electron acceptors in geminal or vicinal position
Rehse, Klaus,Herpel, Martin
, p. 104 - 110 (2007/10/03)
Twenty-two nitroso compounds with cyano, acyloxy, or carbonyl groups in geminal position were prepared eight of them for the girst time. In the solid state these compounds dimerize to colorless azodioxides. Exceptions arethe 4- nitrobenzoyloxynitroso comp
