99114-68-8

Usage

Uses

Used in Recreational Drug Use:
3-MMC is used as a recreational drug for its stimulant effects, which include increased energy, a sense of euphoria, and enhanced sociability. Its popularity in the club and rave scene is attributed to these effects, which are similar to those of MDMA.
Used in Research:
In scientific contexts, 3-MMC may be used as a research chemical to study the effects of synthetic cathinones on the human body and brain. This can help in understanding the mechanisms of action and potential risks associated with the use of such substances.

InChI:InChI=1/C8H18N2/c1-9-5-4-8-10-6-2-3-7-10/h9H,2-8H2,1H3

Upstream product

• 138357-04-7 N-(3-formamidopropyl)pyrrolidine 
• 23159-07-1 3-(1-pyrrolidinyl)propylamine 

Downstream Products

• 138357-07-0 2-(3,4-Dichloro-phenyl)-N-methyl-N-(3-pyrrolidin-1-yl-propyl)-acetamide 
• 138356-36-2 [2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(3-pyrrolidin-1-yl-propyl)-amine 
• 153905-88-5 2-(3,4-Dichloro-phenyl)-N-methyl-N-{3-[methyl-(3-pyrrolidin-1-yl-propyl)-amino]-propyl}-acetamide 
• 153905-86-3 3,4-Dichloro-N-methyl-N-{2-[methyl-(3-pyrrolidin-1-yl-propyl)-amino]-ethyl}-benzamide 

Relevant academic research and scientific papers

Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: Structural requirements and binding affinity at the σ receptor

By synthesizing and testing a part-structure, N-[2-(3,4- dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethylamine (3), derived from our previously reported high affinity σ receptor ligands (1S,2R)-(-)-N-[2- (3,4-dichlorophenyl)-ethyl]-N-methyl-2-(1-pyrrolidinyl)cyclohexylamine [(-)- 2] and (+)-2, we have identified a novel class of superpotent (subnanomolar affinity) σ ligands specific for the σ receptor labeled by [3H]-(+)-3-PPP. When 3 was tested for its capacity to displace [3H]-(+)-3-PPP from guinea pig brain membranes, it exhibited a K(i) of 0.34 nM, which is better than either of its parent compounds (-)-2 (K(i) = 1.3 nM) and (+)-2 (K(i) = 6.0 nM). Other compounds related to 3 such as N-[2-(3,4-dichlorophenyl)ethyl]-N- methyl-2-(1-homopiperidinyl)ethylamine (19) exhibited K(i) = 0.17 nM ([3H]- (+)-3-PPP). The determinants for high σ receptor affinity of 3 were examined by manipulation of this structure in a number of different ways. The high efficacy of these compounds for the σ receptor, their relative chemical simplicity and ease of synthesis, and their high degree of selectivity identifies N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1- pyrrolidinyl)ethylamine (3) and related compounds as a highly promising base for determination of the functional role of σ receptors as well as the development of novel therapeutic agents.