23159-07-1Relevant articles and documents
Studies of Pendant-arm Macrocyclic Ligands. Part 5. Synthesis of Two Pyridine-containing Penta-aza Macrocycles with Single Pyrrolidinyl Pendant Arms and Characterisation of their Nickel(II) and Copper(II) Complexes. Crystal Structure of Perchlorato-3,7,...
Alcock, Nathaniel W.,Balakrishnan, Karappulli P.,Moore, Peter,Omar, Hadi A. A.
, p. 545 - 550 (1987)
Two new pyridine-containing penta-aza macrocyclic ligands, 7-- and 7--3,7,11,17-tetra-azabicycloheptadeca-1(17),13,15-triene (L1 and L2 respectively) have been prepared, and their nickel(II) and copper(II) complexes of formulae 1)(OClO3)> and 3 (M = Ni or Cu, L = L1 or L2) have been isolated and characterised.In the octahedral complex 1)(OClO3)> the presence of a co-ordinated perchlorate group has been established by X-ray crystallography, and the macrocyclic ligand found to co-ordinate close to the corners of a square pyramid with the pendant pyrrolidinyl group at the apical position.
NITROGEN-CONTAINING COMPOUNDS SUITABLE FOR USE IN THE PRODUCTION OF POLYURETHANES
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Paragraph 0275; 0276, (2018/07/31)
The present invention provides for the use of nitrogen compounds of formula (I) and/or of corresponding quaternized and/or protonated compounds for production of polyurethanes, compositions containing these compounds and polyurethane systems, especially polyurethane foams, which have been obtained using the compounds.
Design, synthesis and evaluation of 4-dimethylamine flavonoid derivatives as potential multifunctional anti-Alzheimer agents
Luo, Wen,Wang, Ting,Hong, Chen,Yang, Ya-Chen,Chen, Ying,Cen, Juan,Xie, Song-Qiang,Wang, Chao-Jie
supporting information, p. 17 - 26 (2016/07/06)
A new series of 4-dimethylamine flavonoid derivatives were designed and synthesized as potential multifunctional anti-Alzheimer agents. The inhibition of cholinesterase activity, self-induced β-amyloid (Aβ) aggregation, and antioxidant activity by these derivatives was investigated. Most of the compounds exhibited potent acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity. A Lineweaver-Burk plot and molecular modeling study showed that these compounds targeted both the catalytic active site (CAS) and peripheral anionic site (PAS) of AChE. The derivatives showed potent self-induced Aβ aggregation inhibition and peroxyl radical absorbance activity. Moreover, compound 6d significantly protected PC12 neurons against H2O2-induced cell death at low concentrations. Thus, these compounds could become multifunctional agents for further development for the treatment of AD.
