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(+)-(3R,4R)-BIS(DIPHENYLPHOSPHINO)-1-BENZYLPYRROLIDINE(1,5-CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE is a chiral catalyst that contains rhodium (I) tetrafluoroborate as the central metal atom. It is stabilized by the chelating ligands (3R,4R)-BIS(DIPHENYLPHOSPHINO)-1-BENZYLPYRROLIDINE and 1,5-CYCLOOCTADIENE, which provide the necessary stereoselectivity for the hydrogenation process. This complex is commonly used in asymmetric hydrogenation reactions and has found wide application in synthetic organic chemistry for the preparation of chiral compounds with high enantiomeric excess.
Used in Pharmaceutical Industry:
(+)-(3R,4R)-BIS(DIPHENYLPHOSPHINO)-1-BENZYLPYRROLIDINE(1,5-CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE is used as a chiral catalyst for asymmetric hydrogenation reactions in the synthesis of chiral compounds with high enantiomeric excess. This is crucial for the production of enantiomerically pure pharmaceuticals, as the biological activity and safety of chiral drugs can be highly dependent on their stereochemistry.
Used in Fine Chemicals Industry:
In the fine chemicals industry, (+)-(3R,4R)-BIS(DIPHENYLPHOSPHINO)-1-BENZYLPYRROLIDINE(1,5-CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE is used as a chiral catalyst for the production of enantiomerically pure compounds with high enantioselectivity. This is important for the synthesis of fragrances, flavors, and other specialty chemicals where the stereochemistry of the product can significantly impact the desired properties and performance.
Used in Agrochemical Industry:
(+)-(3R,4R)-BIS(DIPHENYLPHOSPHINO)-1-BENZYLPYRROLIDINE(1,5-CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE is employed as a chiral catalyst in the synthesis of enantiomerically pure agrochemicals. The stereochemistry of these compounds can affect their efficacy, selectivity, and environmental impact, making the use of this catalyst essential for the development of effective and sustainable agrochemical products.
Used in Research and Development:
In research and development, (+)-(3R,4R)-BIS(DIPHENYLPHOSPHINO)-1-BENZYLPYRROLIDINE(1,5-CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE is used as a chiral catalyst for asymmetric hydrogenation reactions to explore new synthetic routes and develop novel chiral compounds. This can lead to the discovery of new pharmaceuticals, agrochemicals, and other specialty chemicals with improved properties and performance.

99143-48-3

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99143-48-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 99143-48-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,1,4 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 99143-48:
(7*9)+(6*9)+(5*1)+(4*4)+(3*3)+(2*4)+(1*8)=163
163 % 10 = 3
So 99143-48-3 is a valid CAS Registry Number.

99143-48-3 Well-known Company Product Price

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  • Aldrich

  • (672777)  (+)-1-Benzyl-[(3R,4R)-bis(diphenylphosphino)]pyrrolidine(1,5-cyclooctadiene)rhodium(I)tetrafluoroborate  98%

  • 99143-48-3

  • 672777-500MG

  • 5,143.32CNY

  • Detail

99143-48-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name [(3R,4R)-1-benzyl-4-diphenylphosphanylpyrrolidin-3-yl]-diphenylphosphane,cycloocta-1,5-diene,rhodium,tetrafluoroborate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

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Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:99143-48-3 SDS

99143-48-3Downstream Products

99143-48-3Relevant academic research and scientific papers

Enantioselective Catalysis, 4. Synthesis of N-Substituted (R,R)-3,4-Bis(diphenylphosphino)pyrrolidines. The Use of their Rhodium Complexes for the Asymmetric Hydrogenation of α-(Acylamino)acrylic Acid Derivatives

Nagel, Ulrich,Kinzel, Elke,Andrade, Juan,Prescher, Guenter

, p. 3326 - 3343 (2007/10/02)

A simple synthesis of (R,R)-3,4-bis(diphenylphosphino)pyrrolidine (6a) and some N-substituted derivatives 6b-m is described. 6l and 6m are optically active tetraphosphanes, composed of two (R,R)-3,4-bis(diphenylphosphino)pyrrolidine units and a dicarboxylic residue.The structure of the parent compound 6a was determined by X-ray diffraction.From the phosphanes 6a-m the cationic 1,5-cyclooctadiene-bisphosphane-rhodium complexes 7a-m were prepared.The complexes 7l and 7m are ligand bridged bis(rhodium) dications.The complexes 7a-m were used for the asymmetric catalytic hydrogenation of the α-(acylamino)acrylic acid derivatives 9a-l.Enantiomeric excesses up to 100percent were achieved.Between 1 and 70 at the optical yields do not depend on the hydrogen pressure.The substrate/catalyst ratio can be as high as 50000/1.

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