99180-11-7Relevant articles and documents
Iron(III) Chloride/Dialkyl Diselenides-Promoted Cascade Cyclization of ortho-Diynyl Benzyl Chalcogenides
do Carmo Pinheiro, Roberto,Back, Davi F.,Zeni, Gilson
supporting information, p. 1866 - 1873 (2019/03/08)
Treatment of ortho-diynyl benzyl chalcogenides with a mixture of iron(III) chloride and diorganyl diselenides led to functionalized chalcogen isochromene-fused chalcogenophene derivatives. The reaction parameters were studied and the results indicated tha
Catalytic chemical amide synthesis at room temperature: One more step toward peptide synthesis
Mohy El Dine, Tharwat,Erb, William,Berhault, Yohann,Rouden, Jacques,Blanchet, Jér?me
, p. 4532 - 4544 (2015/05/13)
An efficient method has been developed for direct amide bond synthesis between carboxylic acids and amines via (2-(thiophen-2-ylmethyl)phenyl)boronic acid as a highly active bench-stable catalyst. This catalyst was found to be very effective at room temperature for a large range of substrates with slightly higher temperatures required for challenging ones. This methodology can be applied to aliphatic, α-hydroxyl, aromatic, and heteroaromatic acids as well as primary, secondary, heterocyclic, and even functionalized amines. Notably, N-Boc-protected amino acids were successfully coupled in good yields with very little racemization. An example of catalytic dipeptide synthesis is reported.
Tandem Pummerer-Diels-Alder reaction sequence. A novel cascade process for the preparation of 1-arylnaphthalene lignans
Padwa, Albert,Cochran, John E.,Kappe, C. Oliver
, p. 3706 - 3714 (2007/10/03)
The α-thiocarbocation generated from the Pummerer reaction of an o-benzoyl-substituted sulfoxide is intercepted by the adjacent keto group to produce an α-thio isobenzofuran as a transient intermediate which undergoes a subsequent Diels-Alder cycloadditio
