99185-29-2 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 10 carbon (C), 9 hydrogen (H), 1 nitrogen (N), and 5 oxygen (O) atoms.
Explanation
This structure consists of a benzene ring with two oxygen atoms (O) forming a dioxole group at positions 1 and 3, a carboxylic acid group (-COOH) at position 5, and an acetamino group (-NHCOCH3) at position 6.
Explanation
The compound is derived from the benzodioxole structure, which is a benzene ring with two oxygen atoms forming a dioxole group.
Explanation
It is commonly used as an intermediate in the synthesis of various drugs, particularly those with anti-inflammatory and analgesic properties.
Explanation
The compound has potential therapeutic applications due to its ability to reduce inflammation and alleviate pain.
Explanation
It serves as a building block for the synthesis of certain pharmaceuticals, particularly those involved in the treatment of pain and inflammation.
Explanation
The compound has been studied for its potential use in the development of new drugs for various medical conditions, indicating its versatility and importance in the pharmaceutical industry.
Chemical Structure
1,3-Benzodioxole-5-carboxylic acid, 6-acetamino-
Derivative of Benzodioxole
Yes
Pharmaceutical Industry Use
Intermediate in drug synthesis
Therapeutic Applications
Anti-inflammatory and analgesic properties
Building Block for Pharmaceutical Synthesis
Yes
Potential Use in Drug Development
Yes
Check Digit Verification of cas no
The CAS Registry Mumber 99185-29-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,1,8 and 5 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 99185-29:
(7*9)+(6*9)+(5*1)+(4*8)+(3*5)+(2*2)+(1*9)=182
182 % 10 = 2
So 99185-29-2 is a valid CAS Registry Number.
99185-29-2Relevant articles and documents
Synthetic applications of Pd(II)-catalyzed C-H carboxylation and mechanistic insights: Expedient routes to anthranilic acids, oxazolinones, and quinazolinones
Giri, Ramesh,Lam, Jonathan K.,Yu, Jin-Quan
supporting information; experimental part, p. 686 - 693 (2010/03/25)
A Pd(II)-catalyzed reaction protocol for the carboxylation of ortho-C-H bonds in anilides to form N-acyl anthranilic acids has been developed. This reaction procedure provides a novel and efficient strategy for the rapid assembly of biologically and pharmaceutically significant molecules, such as benzoxazinones and quinazolinones, from simple anilides without installing and removing an external directing group. The reaction conditions are also amenable to the carboxylation of N-phenyl pyrrolidinones. A monomeric palladacycle containing p-toluenesulfonate as an anionic ligand has been characterized by X-ray crystallography, and the crucial role of p-toluenesulfonic acid in the activation of C-H bonds in the presence of carbon monoxide is discussed. Identification of two key intermediates, a mixed anhydride and benzoxazinone formed by reductive elimination from organometallic Ar(CO)Pd(II)-OTs species, provides mechanistic evidence for a dual-reaction pathway.
