99199-54-9

Usage

Uses

Used in Pharmaceutical Research:
2H-1-Benzopyran-2-carboxylic acid, 6-bromo-3,4-dihydrois used as a building block for the synthesis of various pharmaceutical products. Its potential biological activities, such as anti-inflammatory, antioxidant, and anti-cancer properties, make it a valuable compound for the development of new drugs and therapies.
Used in Agrochemical Research:
2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 6-BROMO-3,4-DIHYDROis also used as a building block in the synthesis of various agrochemical products. Its potential applications in this field can contribute to the development of new and effective agrochemicals for agricultural and environmental purposes.
Used in Chemical Research:
2H-1-Benzopyran-2-carboxylic acid, 6-bromo-3,4-dihydrois used in chemical research for its potential applications in the development of new compounds and materials. Its unique structure and properties make it a promising candidate for further exploration and utilization in various chemical processes.

Upstream product

• 118-93-4 o-hydroxyacetophenone 
• 14736-31-3 ethyl 4-oxo-4H-1-benzopyran-2-carboxylate 
• 24698-77-9 ethyl Chroman-2-carboxylate 
• 474111-16-5 isobutyl (2R)-6-bromo-3,4-dihydro-2H-chromene-2-carboxylate 
• 51939-71-0 chroman-2-carboxylic acid 
• 1216183-10-6 6-bromochroman-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS

The present disclosure relates to compounds suitable for treating, ameliorating and/or preventing neuromuscular disorders, including the reversal of drug-induced neuromuscular blockade. The compounds as defined herein can inhibit the CIC-1 ion channel.

CHROMANE MONOBACTAM COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS

The present invention relates to monobactam compounds of Formula (I) and pharmaceutically acceptable salts thereof. The present invention also relates to compositions which comprise a monobactam compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of the invention, either alone or in combination with a therapeutically effective amount of a second beta-lactam antibiotic.

Preparation method of chromanone 2-carboxylic acid or chroman 2-carboxylic acid derivatives

The present invention relates to a chromanone-2-carboxylic acid derivative and a chroman-2-carboxylic acid derivative which can be used as an intermediate for effective medicinal components currently available in the market, and to preparation methods the

An efficient and practical enantiospecific synthesis of methyl chromanone- and chroman-2-carboxylates

Chromanone-2-carboxylates and chroman-2-carboxylates are useful building blocks for the synthesis of a variety of bioactive compounds, such as repinotan, fidarestat, and nebivolol. An efficient and practical enantiospecific synthesis of chromanone-2-carboxylates and chroman-2-carboxylates has been accomplished using intramolecular Mitsunobu etherification of methyl (S)-2-hydroxy-4-oxo-4-(2′-hydroxy)phenylbutanoates derived from l-malic acid.

Synthesis of some novel N-alkyl/acyl/aroyl 2-(chroman/6-bromochroman-2-yl)- 1H-benzimidazoles using ionic liquids and their antibacterial activity

(Chemical Presented) Synthesis of some novel N-substituted 2-(chroman/6-bromochroman-2-yl)-1H-benzimidazoles by the condensation of 3,4-dihydro-2H-chroman-2-carboxylic acid and 6-bromo-3,4-dihydro-2H-chroman-2- carboxylic acid with o-phenylenediamine in ionic liquid (IL) [bmim]BF 4 and subsequent reactions at the benzimidazole-NH with different types of electrophiles in ILs [bmim]BF4 = 1-butyl-3-methylimidazolium tetrafluoroborate, [bmim]PF6 = 1-butyl-3-methylimidazolium hexafluorophosphate and [buPy]BF4 = butylpyridinium tetrafluoroborate in the presence of sodium hydroxide as a base have been reported. All the synthesized compounds were screened for their antibacterial activity. Some compounds exhibited promising antibacterial activity against Staphylococcus aureus and Salmonella typhimurium when compared to Cephalexin as a reference standard.

2,6-Substituted chroman derivatives useful as beta-3 adrenoreceptor agonists

This invention relates to novel 2,6-substituted chroman derivatives which are useful in the treatment of beta-3 adrenoreceptor-mediated conditions.