24698-77-9

Usage

Uses

Used in Food Industry:
2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-, ethyl ester is used as a flavoring agent for its sweet, floral aroma, enhancing the sensory appeal of food products and contributing to a more enjoyable consumer experience.
Used in Cosmetic Industry:
In the cosmetic industry, 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-, ethyl ester serves as a fragrance ingredient, adding a pleasant scent to products such as perfumes, lotions, and creams. Its aromatic properties help create a more attractive and enjoyable product for consumers.
Used in Perfumery:
2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-, ethyl ester is used as a key ingredient in the production of perfumes, where its sweet, floral scent contributes to the overall fragrance profile. It helps create a unique and appealing scent that can be used in a variety of perfume formulations.
Used in Other Scent Applications:
Beyond the food and cosmetic industries, 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-, ethyl ester is also utilized in other scent applications, such as air fresheners, candles, and cleaning products. Its aromatic properties enhance the sensory experience of these consumer goods, making them more appealing to users.

Upstream product

• 51939-71-0 chroman-2-carboxylic acid 
• 14736-31-3 ethyl 4-oxo-4H-1-benzopyran-2-carboxylate 
• 7664-93-9 sulfuric acid 
• 118-93-4 o-hydroxyacetophenone 
• 64-17-5 ethanol 

Downstream Products

• 137590-28-4 ethyl 2,3-dihydrobenzopyran-(2R)-carboxylate 
• 83278-86-8 3,4-dihydro-2H-1-benzopyran-2-methanol 
• 99199-77-6 rac-ethyl 2-methylchroman-2-carboxylate 
• 137590-29-5 (-)-(R)-3,4-dihydro-2H-1-benzopyran-2-methanol 
• 137590-31-9 (2R)-benzyl-2,3-dihydrobenzopyran 
• 137590-30-8 (R)-(-)-2-<<(Trifluoromethanesulfonyl)oxy>methyl>-2,3-dihydrobenzopyran 
• 51939-71-0 chroman-2-carboxylic acid 
• 83780-47-6 (-)-(R)-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 
• 169747-89-1 (+)-3,4-dihydro-2H-1-benzopyran-2-carboxaldehyde 
• 1451408-58-4 (R)-methyl chroman-2-carboxylate 

Relevant academic research and scientific papers

Umpolung Strategy for Arene C?H Etherification Leading to Functionalized Chromanes Enabled by I(III) N-Ligated Hypervalent Iodine Reagents

The direct formation of aryl C?O bonds via the intramolecular dehydrogenative coupling of a C?H bond and a pendant alcohol represents a powerful synthetic transformation. Herein, we report a method for intramolecular arene C?H etherification via an umpoled alcohol cyclization mediated by an I(III) N-HVI reagent. This approach provides access to functionalized chromane scaffolds from primary, secondary and tertiary alcohols via a cascade cyclization-iodonium salt formation, the latter providing a versatile functional handle for downstream derivatization. Computational studies support initial formation of an umpoled O-intermediate via I(III) ligand exchange, followed by competitive direct and spirocyclization/1,2-shift pathways. (Figure presented.).

CHROMANE MONOBACTAM COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS

The present invention relates to monobactam compounds of Formula (I) and pharmaceutically acceptable salts thereof. The present invention also relates to compositions which comprise a monobactam compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of the invention, either alone or in combination with a therapeutically effective amount of a second beta-lactam antibiotic.

Model Reactions for the Enantioselective Synthesis of γ-Rubromycin: Stereospecific Intramolecular Photoredox Cyclization of an ortho-Quinone Ether to a Spiroacetal

A model study for the enantioselective total synthesis of γ-rubromycin has revealed a promising approach for constructing the chiral, nonracemic bicyclic spiroacetal via the stereospecific photoredox reaction of 1,2-naphthoquinone ether.

Synthesis of some novel N-alkyl/acyl/aroyl 2-(chroman/6-bromochroman-2-yl)- 1H-benzimidazoles using ionic liquids and their antibacterial activity

(Chemical Presented) Synthesis of some novel N-substituted 2-(chroman/6-bromochroman-2-yl)-1H-benzimidazoles by the condensation of 3,4-dihydro-2H-chroman-2-carboxylic acid and 6-bromo-3,4-dihydro-2H-chroman-2- carboxylic acid with o-phenylenediamine in ionic liquid (IL) [bmim]BF 4 and subsequent reactions at the benzimidazole-NH with different types of electrophiles in ILs [bmim]BF4 = 1-butyl-3-methylimidazolium tetrafluoroborate, [bmim]PF6 = 1-butyl-3-methylimidazolium hexafluorophosphate and [buPy]BF4 = butylpyridinium tetrafluoroborate in the presence of sodium hydroxide as a base have been reported. All the synthesized compounds were screened for their antibacterial activity. Some compounds exhibited promising antibacterial activity against Staphylococcus aureus and Salmonella typhimurium when compared to Cephalexin as a reference standard.

A highly efficient enantioselective synthesis of 2-methyl chromans via four sequential palladium-catalyzed reactions

An enantioselective synthesis of substituted 2-methyl chromans was accomplished in four steps using four sequential Pd-catalyzed reactions. A study of the key palladium-catalyzed regioselective aryl ether ring formation of two different substrates was also carried out to better understand the factors which affect the selectivity of the reaction.

Benzopyran derivatives having leukotriene-antagonistic action

The present invention relates to novel 4-oxo-4H-1-benzopyran compounds containing benzyloxymethyl, 3-phenylpropyl, or other araliphatic substituents in their 8-position. These compounds show a leukotriene-antagonistic activity. The compounds are characterized by good oral adsorption. The compounds of the present invention may be used as anti-inflammatory and antiallergic medicaments, and in the treatment of cardiovascular diseases.

Process and intermediates for 2R-benzyl-chroman-6-carbaldehyde

Optically active (C1 -C3) alkyl 2R-chroman-2-carboxylates are prepared by partial hydrolysis of the corresponding racemic ester using a microbial lipase as catalyst. Said 2R-chromancarboxylate is converted via novel 2R-(hydroxymethyl) chroman, 2R-(trifluoromethylsulfonyloxymethyl) chroman and 2R-benzylchroman intermediates into 2R-benzylchroman-6-carbaldehyde, a compound of known utility in the manufacture of certain hypoglycemic agents.