99221-28-0

Basic information

• Product Name: 4-(4-methoxybenzoyl)-4-methylcyclohexa-2,5-dienone
• Synonyms: 4-(4-methoxybenzoyl)-4-methylcyclohexa-2,5-dienone
• CAS NO: 99221-28-0
• Molecular Weight: 242.274
• Mol File: 99221-28-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-methoxybenzoyl)-4-methylcyclohexa-2,5-dienone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-methoxybenzoyl)-4-methylcyclohexa-2,5-dienone(99221-28-0)
• EPA Substance Registry System: 4-(4-methoxybenzoyl)-4-methylcyclohexa-2,5-dienone(99221-28-0)

Safety Data

• Hazardous Substances Data: 99221-28-0(Hazardous Substances Data)

Upstream product

• 99234-40-9 1-trimethylsilyloxy-4-(4-methoxybenzoyl)-4-methylcyclohexa-1,5-diene 
• 6230-72-4 1-(4-methoxyphenyl)-2-methylprop-2-en-1-one 
• 99221-35-9 4-(4-methoxybenzoyl)-4-methylcyclohex-2-enone 
• 121-97-1 4-Methoxypropiophenone 
• 99234-43-2 (2-Methoxy-1-methyl-4-trimethylsilanyloxy-cyclohex-3-enyl)-(4-methoxy-phenyl)-methanone 

Downstream Products

• 106-44-5 p-cresol 
• 100-09-4 4-methoxybenzoic acid 
• 22921-10-4 p-cresyl isopropyl ether 

Relevant articles and documents

Synthesis of 4-Benzoyl-4-methylcyclohexa-2,5-dienone and its Benzoyl Substitued Derivatives: Isolated 4-Acylcyclohexa-2,5-dienones

The synthesis are reported of 4-benzoyl-4-methylcyclohexa-2,5-dienone, and its 4-(4-chlorobenzoyl) and 4-(4-methoxybenzoyl) analogues.These are the first isolated 4-acylcyclohexa-2,5-dienones containing the dienone function in a monocyclic ring system.All are sensitive to nucleophilic attack at the benzoyl carbonyl group, being cleaved to 4-methylphenol and its derivatives of the appropriate substitued benzoic acid.Treatment with acids failed to give the desired dienone-phenol rearrangement, with a benzoyl migration from C-4 to C-3, but instead gave 4-methylphenyl benzoate or its derivatives, by a reversal of a Fries rearrangement with C-4 to O-aroyl migration.