99259-43-5Relevant academic research and scientific papers
Catalytic asymmetric addition of thiols to nitrosoalkenes leading to chiral non-racemic α-sulfenyl ketones
Hatcher, John M.,Kohler, Mark C.,Coltart, Don M.
supporting information; experimental part, p. 3810 - 3813 (2011/09/16)
The first asymmetric organocatalytic sulfenylation of in situ derived nitrosoalkenes leading to chiral nonracemic α-sulfenylated ketones is described. The transformation proceeds in an umpolung fashion, relative to enolate/azaenolate methods, and uses simple thiols, thereby obviating the need for electrophilic sulfur reagents.
