99261-08-2Relevant articles and documents
ENANTIOSPECIFIC TOTAL SYNTHESIS OF (-)-MEGAPHONE BY A HIGHLY CONTROLLED CONSECUTIVE 1,4- AND 1,3-ASYMMETRIC INDUCTION.
Tomioka, Kiyoshi,Kawasaki, Hisashi,Iitaki, Yoichi,Koga, Kenji
, p. 903 - 906 (1985)
Enantiospecific total synthesis of (-)-megaphone (1) is reported.The key synthetic tactic is the use of (4S)-2Z-ethylidene-4-trityloxymethyl-butan-4-olide (6) to both establish the relative and absolute stereochemistry of the contiguous tertiary and quate