99267-71-7

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 87-91-2 diethyl (2R,3R)-tartrate 
• 25226-98-6 trans-cinnamaldehyde diethylacetal 

Downstream Products

• 133179-03-0 (1R,3S,4S,6S)-6-Benzyl-3-methyl-2,7-dioxa-bicyclo[2.2.1]heptane 
• 133269-17-7 (1R,3S,4S,6R)-6-Benzyl-3-methyl-2,7-dioxa-bicyclo[2.2.1]heptane 
• 133179-09-6 1-((2S,4R)-4-Benzyl-tetrahydro-furan-2-yl)-ethanone 
• 133179-06-3 1-((2S,4S)-4-Benzyl-tetrahydro-furan-2-yl)-ethanone 
• 126434-64-8 (R)-dihydro-4-(phenylmethyl)furan-2(3H)-one 
• 126434-65-9 (S)-(-)-β-benzyl-γ-butyrolactone 
• 75332-40-0 C₂₇H₂₈O₈S₂ 
• 133179-02-9 (4R,5R)-4,5-Bis-bromomethyl-2-((E)-styryl)-[1,3]dioxolane 
• 133179-07-4 (2R,5S)-5-Benzyl-2-methyl-dihydro-pyran-3-one 
• 133179-08-5 (S)-1-((2S,4R)-4-Benzyl-tetrahydro-furan-2-yl)-ethanol 
• 110919-14-7 (4R,6R)-4,6-Dimethyl-2-((1R,2R)-2-phenyl-cyclopropyl)-[1,3]dioxane 
• 82263-48-7 trans-2- phenylcyclopropane-1-carbaldehyde 
• 3471-10-1 (1R,2R)-trans-2-phenyl-1-cyclopropanecarboxylic acid 
• 133179-00-7 [(4S,5S)-5-Hydroxymethyl-2-((E)-styryl)-[1,3]dioxolan-4-yl]-methanol 

Relevant academic research and scientific papers

A New Methodology for the Construction of Chiral 4-Benzyl-2-furanone via C2-Symmetric Bis-Radical Intermediate

A new methodology leading to optically pure 4-benzyl-2-furanone has been developed by employing intramolecular reaction intervening C2-Symmetric bis-radical intermediate derived from diethyl (L)-tartrate.

ASYMMETRIC SIMMONS-SMITH REACTIONS USING HOMOCHIRAL PROTECTING GROUPS

Asymmetric Simmons-Smith reactions of α,β-unsaturated acetals derived from chiral dialkyl tartrate or (2R,4R)-2,4-pentanediol are described.Treatment of the acetal with diethylzinc and methylene iodide gives a cyclopropane with high diastereoselectivity.The acetal group is readily transformed to the aldehyde or the ester group.In addition, the method is successfully applied to the enantioselective synthesis of 5,6-methanoleukotriene A4, a stable and selective inhibitor of leukotriene biosynthesis.