99295-22-4

Upstream product

• 1427166-47-9 (S)-ethyl 1-((S)-2-((tert-butoxycarbonyl)amino)-3-phenylpropanoyl)pyrrolidine-2-carboxylate 
• 514214-66-5 (S)-tert-butyl (1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 1161-13-3 N-Cbz-L-Phe 
• 99215-68-6 Z-Phe-D-Pro-OEt 

Downstream Products

• 99266-69-0 Boc-Orn(Z)-Leu-Orn(Z)-Phe-D-Pro-NHNH₂ 
• 99215-77-7 Boc-Orn(Z)-Leu-Orn(Z)-Phe-D-Pro-OEt 
• 1173882-19-3 (6S,9S,12S,14aS,20S,23S,25aS)-20-benzyl-6,12-di((S)-sec-butyl)-9-(hydroxymethyl)-23-isobutylhexadecahydro-1H-dipyrrolo[1,2-a:1',2'-j][1,4,7,10,13,16,19]heptaazacyclohenicosine-5,8,11,14,19,22,25(25aH)heptaone 
• 1427166-55-9 (S)-2-(((S)-1-(((S)-1-((S)-2-(ethoxycarbonyl)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-ium chloride 
• 1427166-58-2 (S)-1-((S)-2-((S)-2-((S)-1-((6S,9S,12S)-9-((benzyloxy)methyl)-6,12-di((S)-sec-butyl)-2,2-dimethyl-4,7,10-trioxo-3-oxa-5,8,11-triazatridecan-13-oyl)pyrrolidine-2-carboxamido)-4-methylpentanamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid 
• 1427166-56-0 (2S,3S)-1-(((S)-3-(benzyloxy)-1-(((2S,3S)-1-((S)-2-(((S)-1-(((S)-1-((S)-2-carboxypyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-3-methyl-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxopentan-2-aminium chloride 
• 1427166-57-1 ((6S,9S,12S,14aS,20S,23S,25aS)-20-benzyl-6,12-di((S)-sec-butyl)-23-isobutyl-5,8,11,14,19,22,25-heptaoxotetracosahydro-1H-dipyrrolo[1,2-a:1',2'-j][1,4,7,10,13,16,19]heptaazacyclohenicosin-9-yl)methyl benzoate 
• 1427166-52-6 (S)-ethyl 1-((S)-2-((S)-2-((S)-1-((6S,9S,12S)-9-((benzyloxy)methyl)-6,12-di((S)-sec-butyl)-2,2-dimethyl-4,7,10-trioxo-3-oxa-5,8,11-triazatridecan-13-oyl)pyrrolidine-2-carboxamido)-4-methylpentanamido)-3-phenylpropanoyl)pyrrolidine-2-carboxylate 
• 1427166-51-5 (S)-tert-butyl 2-(((S)-1-(((S)-1-((S)-2-(ethoxycarbonyl)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate 
• 99215-71-1 Boc-Orn(Z)-Phe-D-Pro-OEt 

Relevant academic research and scientific papers

Total synthesis of cyclic heptapeptide Rolloamide B

The first total synthesis of Rolloamide B, a cyclic proline-enriched heptapeptide, is reported. This work features solution phase benzotriazole-mediated peptide synthesis ligating native amino acids. The Royal Society of Chemistry 2013.

Syntheses of Cyclic Decapeptides with Four Ornithyl Residues Related to Gramicidin S

Three cyclic decapeptides with four L-ornithyl residues related to gramicidin S (GS), cyclo(-Orn-Leu-Orn-D-Phe-Pro-)2 (D-L-12), cyclo(-Orn-Leu-Orn-Phe-Pro-)2 (L-L-12), and cyclo(-Orn-Leu-Orn-Phe-D-Pro-)2 (L-D-12), were synthesized to investigate the contr