99298-21-2

Upstream product

• 108-24-7 acetic anhydride 
• 99298-13-2 4-(benzyloxy)-3β-ribofuranosylpyrazole-5-carboxamide 
• 100-39-0 benzyl bromide 
• 30868-30-5 pyrazofurin 

Downstream Products

• 133470-98-1 4-O-benzyl-2',3',5'-tri-O-acetylpyrazofurin 
• 99298-24-5 Acetic acid (2S,3S,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(4-benzyloxy-5-thiocarbamoyl-1H-pyrazol-3-yl)-tetrahydro-furan-3-yl ester 
• 99298-25-6 4-(benzyloxy)-3-β-D-ribofuranosylpyrazole-5-thiocarboxamide 
• 133470-97-0 5-amino-3-β-D-ribofuranosylpyrazolo<3,4-e><1,3>oxazin-7-one 
• 133470-90-3 5-amino-1-benzyl-3-β-D-ribofuranosylpyrazolo<3,4-e><1,3>oxazin-7-one 

Relevant academic research and scientific papers

Synthetic approaches to the guanosine and xanthosine analogues 5-amino-3-β-D-ribofuranosylpyrazolo[3,4-e][1,3]oxazin-7-one and 3-β-D-ribofuranosylpyrazolo[3,4-e][1,3]oxazine-5,7-dione and studies of their antitumor potential

5-Amino-3-β-D-ribofuranosylpyrazolo[3,4-e][1,3]oxazin-7-one has been synthesized via cyclization of the appropriately protected pyrazofurin derivatives and subsequent transformations of the hetorocyclic moiety. This guanosine analogue was marginally cytot

Synthesis and biological activity of certain nucleoside and nucleotide derivatives of pyrazofurin

A number of nucleoside and nucleotide derivatives of 4-hydroxy-3-β-D-ribofuranosylpyrazole-5-carboxamide (pyrazofurin, 1) were prepared and tested for their antiviral and cytostatic activity in cell culture. Treatment of 1 with benzyl bromide gave 4-O-ben