99299-71-5Relevant academic research and scientific papers
Biomimetic carbene cascades enabled imine derivative migration from carbene -bearing thiocarbamates
Li, Xue,Chen, Haohua,Xuan, Qingqing,Mai, Shaoyu,Lan, Yu,Song, Qiuling
, p. 3518 - 3523 (2021/05/29)
Inspired by the body circulation of Omeprazole (irreversible proton pump inhibitor), we disclose the carbene-triggered cascades for the synthesis of 2-aminobenzofuran derivatives from N-sulfonyl-1,2,3-triazoles or benzothioazole-bearing thiocarbamates, which represents an unprecedented imine derivative migration process. Furthermore, the desulfurizing reagent-free Barton-Kellogg-type reactions starting from N-sulfonyl-1,2,3-triazoles have also been achieved for the first time, and elemental sulfur is confirmed as a byproduct during this transformation. Both experimental data and DFT calculations further thoroughly explained the unique reactivity.
Halocarbon Chemistry. !. (2-Hydroxyaryl)acetylenes from Haloethyl Aryl Ethers. A New O to C Rearrangement.
Subramanian, Raghupathi,Johnson, Francis
, p. 5430 - 5432 (2007/10/02)
A new base-induced (BuLi) oxygen-to carbon rearrangement is described which involves the direct conversion of phenyl tetra(or tri)haloethyl ethers and the related intermediate phenoxyalkynes to the corresponding 1-(2-hydroxyphenyl)alkynes in good to excel
