99315-29-4Relevant academic research and scientific papers
SYNTHESIS OF AZETIDINES FROM β-CHLORO IMINES
Sulmon, Paul,Kimpe, Norbert De,Schamp, Niceas,Tinant, Bernard,Declercq, Jean-Paul
, p. 3653 - 3670 (2007/10/02)
The reaction of β-chloro imines 4 with potassium cyanide in methanol or with lithium aluminium hydride in dry ether gave rise to 2-cyanoazetidines 5 and azetidines 21.The reaction proceeded by nucleophilic addition of cyanide or hydride across the carbon-
A Novel Synthesis of 2-Cyano-3,3-dimethylazetidines
Sulmon, Paul,Kimpe, Norbert De,Schamp, Niceas
, p. 715 - 716 (2007/10/02)
A new route to 2-cyano-3,3-dimethylazetidines has been developed by reaction of β-chloroimines with potassium cyanide in methanol which involves nucleophilic addition and subsequent intramolecular nucleophilic substitution.
