99333-69-4

Upstream product

• 99333-63-8 (S)-3-((3S,4R)-1-Benzyl-2-oxo-4-phenethyl-azetidin-3-yl)-4-phenyl-oxazolidin-2-one 
• 129829-29-4 (3S,4R)-1-benzyl-3<(S)-4-phenyloxazolidinyl>-4-styrylazetidin-2-one 
• 180072-74-6 (S)-3-[(3S,4R)-1-(Bis-trimethylsilanyl-methyl)-2-oxo-4-phenethyl-azetidin-3-yl]-4-phenyl-oxazolidin-2-one 
• 198021-56-6 [(3S,4R)-1-(Bis-trimethylsilanyl-methyl)-2-oxo-4-phenethyl-azetidin-3-yl]-carbamic acid tert-butyl ester 
• 180072-66-6 (Bis-trimethylsilanyl-methyl)-[3-phenyl-prop-(E)-ylidene]-amine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 104-53-0 3-phenyl-propionaldehyde 
• 80542-40-1 N-cinnamylidene-p-anisidine 
• 213883-23-9 [(3S,4R)-1-(4-Methoxy-phenyl)-2-oxo-4-phenethyl-azetidin-3-yl]-carbamic acid tert-butyl ester 
• 99333-70-7 (3S,4R)-3-Amino-4-phenethyl-azetidin-2-one 

Downstream Products

• 213883-22-8 ((3S,4R)-3-tert-Butoxycarbonylamino-2-oxo-4-phenethyl-azetidin-1-yl)-acetic acid methyl ester 

Relevant academic research and scientific papers

Auswirkungen der Substituenten am Imin auf die -Cycloaddition mit Ketenen

Stichworte: Asymmetrische Synthesen, Cycloadditionen, Imine, β-Lactame

The asymmetric synthesis of β-lactam antibiotics. I. Application of chiral oxazolidones in the Staudinger Reaction

The reactions of oxazolidone with N-benzylimines proceed with exceptional levels of asymmetric induction to form the cycloadducts. Subsequent dissolving metal reduction affords the homochiral β-lactam derivatives in good overall yield.