99333-70-7

Upstream product

• 99333-63-8 (S)-3-((3S,4R)-1-Benzyl-2-oxo-4-phenethyl-azetidin-3-yl)-4-phenyl-oxazolidin-2-one 
• 129829-29-4 (3S,4R)-1-benzyl-3<(S)-4-phenyloxazolidinyl>-4-styrylazetidin-2-one 

Downstream Products

• 129743-86-8 (3S,4R)-4-Phenethyl-3-{[1-phenyl-meth-(E)-ylidene]-amino}-azetidin-2-one 
• 129743-85-7 (3R,4R,8S)-8-Isopropyl-3-phenethyl-7-oxa-2,5-diaza-spiro[3.4]octane-1,6-dione 
• 129743-88-0 [(3R,4R)-3-((S)-1-Hydroxy-2-methyl-propyl)-2-oxo-4-phenethyl-azetidin-3-yl]-carbamic acid ethyl ester 
• 129743-87-9 (3S,4R,1'S)-3-(1'-hydroxy-2'-methyl)propyl-β-lactam 
• 99333-69-4 ((3S,4R)-2-Oxo-4-phenethyl-azetidin-3-yl)-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

ASYMMETRIC SYNTHESIS WITH CHIRAL β-LACTAMS. HIGHLY STEREOSELECTIVE ALKYLATION AND ALDOL REACTION OF A CHIRAL 3-AMINO-4-STYRYL-β-LACTAM

Extremely stereoselective alkylation and aldol reaction of enantiomerically pure 3-amino-4-styryl-β-lactams and a application to the asymmetric synthesis of α,β-diamino acid and alcohol are described.Possible mechanisms for these reactions are proposed.

The asymmetric synthesis of β-lactam antibiotics. I. Application of chiral oxazolidones in the Staudinger Reaction

The reactions of oxazolidone with N-benzylimines proceed with exceptional levels of asymmetric induction to form the cycloadducts. Subsequent dissolving metal reduction affords the homochiral β-lactam derivatives in good overall yield.