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(Z)-3-fluoro-3-phenylacrylaldehyde is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 99337-60-7 Structure
  • Basic information

    1. Product Name: (Z)-3-fluoro-3-phenylacrylaldehyde
    2. Synonyms: (Z)-3-fluoro-3-phenylacrylaldehyde
    3. CAS NO:99337-60-7
    4. Molecular Formula:
    5. Molecular Weight: 150.152
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 99337-60-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (Z)-3-fluoro-3-phenylacrylaldehyde(CAS DataBase Reference)
    10. NIST Chemistry Reference: (Z)-3-fluoro-3-phenylacrylaldehyde(99337-60-7)
    11. EPA Substance Registry System: (Z)-3-fluoro-3-phenylacrylaldehyde(99337-60-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 99337-60-7(Hazardous Substances Data)

99337-60-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 99337-60-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,3,3 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 99337-60:
(7*9)+(6*9)+(5*3)+(4*3)+(3*7)+(2*6)+(1*0)=177
177 % 10 = 7
So 99337-60-7 is a valid CAS Registry Number.

99337-60-7Relevant articles and documents

Effect of Fluorination on Skin Sensitization Potential and Fragrant Properties of Cinnamyl Compounds

Charpentier, Julie,Emter, Roger,Koch, Heinz,Lelièvre, Dominique,Pannecoucke, Xavier,Couve-Bonnaire, Samuel,Natsch, Andreas,Bombrun, Agnes

, (2018/04/27)

A series of three α- and three β-fluorinated representatives of the family of cinnamate-derived odorants (cinnamaldehyde (1), cinnamyl alcohol (2), and ethyl cinnamate (3)) as used as fragrance ingredients is described. Olfactive evaluation shows that the

Gold-Catalyzed Hydrofluorination of Electron-Deficient Alkynes: Stereoselective Synthesis of β-Fluoro Michael Acceptors

O'Connor, Thomas J.,Toste, F. Dean

, p. 5947 - 5951 (2018/07/24)

The gold(I)-catalyzed, stereoselective hydrofluorination of electron-deficient alkynes with triethylamine trihydrogen fluoride (Et3N·3HF) is described. Fluorinated α,β-unsaturated aldehydes, amides, esters, ketones, and nitriles were isolated i

Stereoselective One-Pot Sequential Dehydrochlorination/trans-Hydrofluorination Reaction of β-Chloro-α,β-unsaturated Aldehydes or Ketones: Facile Access to (Z)-β-Fluoro-β-arylenals/β-Fluoro-β-arylenones

Zhang, Jingli,Liu, Liran,Duan, Junxin,Gu, Lianghu,Chen, Bifeng,Sun, Taolei,Gong, Yuefa

supporting information, p. 4348 - 4358 (2017/12/26)

The monofluoroalkene substructure shows a high potential as a fluorinated synthon in organic synthesis. However, control of the Z/E stereoselectivity of multi-substituted monofluoroalkene products in one-pot reactions still remains a challenge. An unprecedented one-pot approach for the highly regio- and stereoselective preparation of functionalized (Z)-β-monofluoro tri-substituted alkenes from readily available β-chloro-α,β-unsaturated aldehydes or ketones has been explored. Mechanistic studies demonstrated that the reaction is initiated by dehydrochlorination of the substrates to give alkynyl aldehydes/ketones, followed by their trans-hydrofluorination. It is worth mentioning that a fluorinating reagent with suitable basicity and nucleophilicity plays a key role in promoting the formation of (Z)-β-fluoro-β-aryl tri-substituted monofluoroalkenes. (Figure presented.).

Characterization of the monolignol oxidoreductase AtBBE-like protein 15 L182V for biocatalytic applications

Pils, Sabine,Schnabl, Kordula,Wallner, Silvia,Daniel, Bastian,Macheroux, Peter,Kljajic, Marko,Kupresanin, Nina,Breinbauer, Rolf,Fuchs, Michael,Rocha, Raquel,Schrittwieser, Joerg H.,Kroutil, Wolfgang

, p. S6 - S14 (2018/04/05)

Monolignol oxidoreductases from the berberine bridge enzyme-like (BBE-like) protein family (pfam 08031) catalyze the oxidation of monolignols to the corresponding aldehydes. In this report, we explore the potential of a monolignol oxidoreductase from Arabidopsis thaliana (AtBBE-like protein 15) as biocatalyst for oxidative reactions. For this study we employed a variant with enhanced reactivity towards oxygen, which was obtained by a single amino acid exchange (L182V). The pH and temperature optima of the purified AtBBE-like protein 15 L182V were determined as well as the tolerance toward organic co-solvents; furthermore the substrate scope was characterized. The enzyme has a temperature optimum of 50 °C and retains more than 50% activity between pH 5 and pH 10 within 5 min. The enzyme shows increased activity in the presence of various co-solvents (10–50% v/v), including acetonitrile, 2-propanol, 1,4-dioxane, and dimethyl sulfoxide. Primary benzylic and primary or secondary allylic alcohols were accepted as substrates. The enantioselectivity E in the oxidation of secondary alcohols was good to excellent (E>34 to?>200).

Mono-hydrofluorination of Electrophilic Alkynes by the Liquid Bishasic CsF-H2O-DMF System (DMF = N,N-dimethylformamide)

Gorgues, Alain,Stephan, Dominique,Cousseau, Jack

, p. 1493 - 1494 (2007/10/02)

CsF induces the addition of HF in fair yields to activated acetylenic triple bonds in a DMF-water bishasic medium (DMF = N,N-dimethylformamide); in a homogeneous DMF-water mixture, no addition is observed.

Tetrabutylammonium and polymer-supported dihydrogentrifluoride: new reagents for the hydrofluorination of activated acetylenic bonds

Cousseau, Jack,Albert, Patrice

, p. 910 - 915 (2007/10/02)

Tetrabutylammonium and polymer-supported dihydrogentrifluoride are easily prepared by a phase-transfer procedure from the corresponding fluoride salts.These stable new dihydrogentrifluoride salts allow the addition of HF under mild conditions to carbon-ca

Tetrabutylammonium and Polymer-supported Dihydrogentrifluoride: New Hydrofluorinating Reagents for Electrophilic Alkynes

Albert, Patrice,Cousseau, Jack

, p. 961 - 962 (2007/10/02)

Tetrabutylammonium and polymer-supported dihydrogentrifluoride are readily accessible reagents which allow addition of HF to activated carbon-carbon triple bonds, thus leading to functional fluoroalkenes in good yields.

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