994-07-0

Basic information

• Product Name: chlorodimethoxymethylsilane
• Synonyms: chlorodimethoxymethylsilane;Dimethoxy(methyl)chlorosilane;Methylchlorodimethoxysilane
• CAS NO: 994-07-0
• Molecular Formula: C₃H₉ClO₂Si
• Molecular Weight: 140.64086
• EINECS: 213-613-5
• Mol File: 994-07-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 75.4°Cat760mmHg
• Flash Point: 2.1°C
• Appearance: /
• Density: 1.019g/cm³
• Vapor Pressure: 116mmHg at 25°C
• Refractive Index: 1.394
• CAS DataBase Reference: chlorodimethoxymethylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: chlorodimethoxymethylsilane(994-07-0)
• EPA Substance Registry System: chlorodimethoxymethylsilane(994-07-0)

Safety Data

• Hazardous Substances Data: 994-07-0(Hazardous Substances Data)

Usage

General Description

Chlorodimethoxymethylsilane is a chemical compound with the molecular formula CH3ClO2Si. It is a colorless liquid that is primarily used as a reagent in organic synthesis and as a crosslinking agent in the manufacturing of silicone polymers. chlorodimethoxymethylsilane is highly reactive due to the presence of a chloro group and can undergo hydrolysis in the presence of moisture to produce hydrogen chloride gas and silanol groups. It is also used as a silylating agent in the modification of surfaces in various industrial applications. Chlorodimethoxymethylsilane should be handled with caution as it is corrosive and can cause irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C3H9ClO2Si/c1-5-7(3,4)6-2/h1-3H3

Upstream product

• 75-79-6 Methyltrichlorosilane 
• 1634-04-4 tert-butyl methyl ether 
• 1185-55-3 Methyltrimethoxysilan 
• 18292-07-4 (dimethoxy)phenylsilane 
• 67-56-1 methanol 

Downstream Products

• 1251196-91-4 o-bromo[dimethoxy(methyl)silyl]benzene 
• 151037-24-0 WI(N₂Si(CH₃)(OCH₃)2){P(CH₃)2C₆H₅}4 
• 475094-86-1 1,4-bis-[(dimethoxy-methyl-silanyl)-ethynyl]-benzene 
• 58666-73-2 Methyldimethoxy-(phenylthio)-silan 
• 58666-74-3 Methyldimethoxy-(benzylthio)-silan 

Relevant articles and documents

Protecting and Leaving Functions of Trimethylsilyl Groups in Trimethylsilylated Silicates for the Synthesis of Alkoxysiloxane Oligomers

The concept of protecting groups and leaving groups in organic synthesis was applied to the synthesis of siloxane-based molecules. Alkoxy-functionalized siloxane oligomers composed of SiO4, RSiO3, or R2SiO2 units were chosen as targets (R: functional groups, such as Me and Ph). Herein we describe a novel synthesis of alkoxysiloxane oligomers based on the substitution reaction of trimethylsilyl (TMS) groups with alkoxysilyl groups. Oligosiloxanes possessing TMS groups were reacted with alkoxychlorosilane in the presence of BiCl3 as a catalyst. TMS groups were substituted with alkoxysilyl groups, leading to the synthesis of alkoxysiloxane oligomers. Siloxane oligomers composed of RSiO3 and R2SiO2 units were synthesized more efficiently than those composed of SiO4 units, suggesting that the steric hindrance around the TMS groups of the oligosiloxanes makes a difference in the degree of substitution. This reaction uses TMS groups as both protecting and leaving groups for SiOH/SiO? groups.

ALTERNATIVE METHODS FOR THE SYNTHESIS OF ORGANOSILICON COMPOUND

A method of forming chloro-substituted silanes from the reaction of an alkoxysilane with a chlorinating agent in the optional presence of a catalyst is provided. More specifically, chloro-substituted silanes, including but not limited to silicon tetrachloride, are formed by reacting a chlorinating agent, such as thionyl chloride, with an alkylalkoxysilane having the formula (R'0)4-xSiRx, where R and R' are independently selected alkyl groups comprising one or more carbon atoms and x is 0, 1, 2, or 3. The catalyst may be dimethylformamide, (chloromethylene)dimethyliminium chloride, or triethylamine, among others. The chloro- substituted silane formed in the reaction along with several by-products has the formula (RO)4-x-ySiRxCly; where x is 0, 1, 2, or 3 and y is 1, 2, 3, or 4. One of the by-products of the reaction is an alkyl chloride.

Synthesis and structures of o-(dihydrosilyl)(dimesitylboryl)benzenes

O-(Dihydrosilyl)(dimesitylboryl)benzenes 1 were prepared in 6 steps. o-Dibromobenzene was mono-lithiated with n-BuLi and reacted with chloro(dimethoxy)silanes to afford o-C6H4(Br)[SiR(OMe) 2] (2) (R = Ph, Me). Bromine-lith