99404-90-7Relevant academic research and scientific papers
Controlled Functionalization in the Cyclopentane Ring Using Organomolybdenum Chemistry
Pearson, Anthony J.,Khan, Md. Nazrul I.
, p. 5276 - 5285 (1985)
The synthesis and reactivity of a series of η3-cycloheptenyl-Mo(CO)2Cp and η4-cycloheptadiene-Mo(CO2)2Cp complexes are reported.The parent ?-allyl complex (η3-C7H11)Mo(CO)2Cp undergoes hydride abstraction on treatment with Ph3CPF6 to give (η4-C7H10)Mo(CO)2Cp cation as the PF6- salt.This complex reacts stereospecifically with a variety of carbon nucleophiles, including Grignard reagents and stabilized enolates, by addition to the diene ligand to give substituted ?-allyl complexes (η3-C7H10R)Mo(CO)2Cp.With the unsymmetrical enolate from methyl 2-oxocyclopentanecarboxylate a high degree of diastereoselectivity is observed.Alkyl-substituted complexes, (η3-C7H10R)Mo(CO)2Cp (R = CH3, CH2CH=CH2, C6H4OMe-p), undergo regiospecific hydride abstraction to give (η4-C7H9R)Mo(CO)2Cp cations which react with a range of nucleophiles stereospecifically at the diene ligand.The regioselectivity of this second nucleophile addition was studied.Decomplexation of the product ?-allyl complexes by a cyclofunctionalization / demetalation procedure is reported.
STEREO- AND REGIO-CONTROLLED FUNCTIONALIZATION OF CYCLOHEPTENE USING ORGANOMOLYBDENUM CHEMISTRY
Pearson, Anthony J.,Khan, Nazrul I.
, p. 1407 - 1410 (2007/10/02)
Cycloheptene is readily converted to the cationic cycloheptadiene-Mo(CO)2Cp complex, which reacts with a range of nucleophiles; hydride abstraction from the product ?-allyl-Mo(CO)2Cp complexes give substituted cycloheptadiene complexes wich react with a second nucleophile stereospecifically, and decomplexation of the ?-allyl complexes gives substituted cycloheptene derivatives with defined relative stereochemistry.
