99414-69-4Relevant articles and documents
Bioactive formylpyrazole analogues: Synthesis, antimicrobial, antioxidant and molecular docking studies
Gurunanjappa, Pavithra,Kameshwar, Vivek Hamse,Kariyappa, Ajay Kumar
, p. 1549 - 1554 (2017)
A series of six new 3-(1-hydroxynaphthalen-2-yl)-1-aryl-1 H-pyrazole-4-carbaldehyde derivatives were synthesized by Vilsmeier-Haack reaction of phenyl hydrazones. The new compounds were characterized by spectral studies and elemental analysis. Synthesized compounds were evaluated in vitro for their antimicrobial and antioxidant susceptibilities. The results suggest that the compounds with methyl and methoxy substitutions in the aromatic ring have good in vitro antimicrobial activities and those with methyl, methoxy and no substitutions possess promising DPPH and hydroxyl free radical scavenging abilities.
HYDRAZONE DERIVATIVES AND THEIR USE AS BETA SECRETASE INHIBITORS
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Page/Page column 17; 25, (2008/06/13)
The invention relates to compounds having the general formula (I) wherein R3 is selected from the group consisting of H, methyl and hydroxyalkyl, and wherein Z1 and Z2are selected independently from one another from the gr
