99422-82-9Relevant academic research and scientific papers
Para substituted benzaldehydes as expedient reagents for the oxidative aromatization of hydroquinoline
Majumdar, Poulomi,Pati, Anita,Behera, Rajani K.,Behera, Ajaya Kumar
, p. 703 - 712 (2013/07/05)
A Cannizzaro-type reaction of tetrahydro-5(1H)-quinolinones with para substituted benzaldehydes in the presence of a base formed the corresponding quinoline and aryl methanol rather than arylidene derivatives because of the oxidation of tetrahydroquinoline and reduction of benzaldehydes as a result of unprecedented hydride transfer from tetrahydroquinoline to arylaldehydes. The reaction proceeds best with the participation of substituents with +M effect in substrate molecule.
Automated parallel synthesis of chalcone-based screening libraries
Powers, David G.,Casebier, David S.,Fokas, Demosthenes,Ryan, William J.,Troth, Jonah R.,Coffen, David L.
, p. 4085 - 4096 (2007/10/03)
Using a variety of condensation and cyclization reactions, nine combinatorial arrays of individual chalcone derivatives, over 74,000 in all, were produced in 50 μM quantities. The ease with which a broad range of diversity can be fabricated around a single molecular motif using automated parallel solution phase synthesis has been demonstrated.
HETEROCYCLIZATION OF TRIKETONES OF THE 2-(3-OXOPROPYL)CYCLOHEXANE-1,3-DIONE SERIES
Kharchenko, V. G.,Markova, L. I.,Kazarinova, T. D.,Yudovich, L. M.
, p. 758 - 761 (2007/10/02)
Triketones of the 2-(3-oxopropyl)cyclohexane-1,3-dione series have been shown for the first time to react with boron trifluoride etherate to give the novel 5-oxo-5,6,7,8-tetrahydrochromylium fluoroborates, which in turn react with ammonia to give 5-oxo-5,
