130716-55-1Relevant articles and documents
A convenient synthesis of 2,4-diarylpolyhydroquinoline derivations in the presence of ammonium acetate
Wang, Xiang-Shan,Shi, Da-Qing,Tu, Shu-Jiang
, p. 3449 - 3454 (2002)
A series of substituted 5-oxo-1,2,3,4,5,6,7,8-octahydroquinoline derivatives have been synthesized from 5,5-dimethyl-1,3-cyclohexane-dione (dimedone) and 1,3-diaryl-2-propen-1-one in DMF at 80°C in the presence of ammonium acetate with high yields (64-98%
Synthesis and crystal structure of 7,7-dimethyl-2,4-diphenyl-5-oxo-1,4,5,6,7,8-hexahydroquinolin
Wang, Xiangshan,Shi, Daqing,Tu, Shujiang
, p. 381 - 384 (2002)
The 7,7-dimethyl-2,4-diphenyl-5-oxo-1,4,5,6,7,8-hexahydroquinolin was synthesized and the compound was identified by IR, 1H NMR, elemental analysis and X-ray crystallography. It crystallized in the triclinic space group P1, with a = 7.129(2) A, b = 10.514(3) A, c = 13.040(3) A, α = 76.58(2)°, β = 88.97(2)°, γ = 79.24(2)°, and Dcalc = 1.172 g cm-3 for Z = 2. X-ray analysis revealed that the atoms C(2), C(3), C(4), C(10), C(9), and N form a six-membered ring that adopts a boat conformation, and another six-membered ring (C(10)-C(9)-C(8)-C(7)-C(6)-C(5)) adopts a half-chair conformation. In addition, there is an intermolecular hydrogen bond (N-H0 ... O) in the product molecule.
Regiospecific ring closure reactions of 1, 3-diphenylthiobarbituric acid and dimedone: Formation of spiro vs fused heterocycles
Pati, Anita,Majumdar, Poulomi,Garnayak, Sarita,Behera, Ajaya K.,Behera, Rajani K.
, p. 384 - 391 (2014/05/06)
The one pot reaction of 1, 3-diphenylthiobarbituric acid with benzylidene acetophenone, benzaldehyde and ammonium acetate in presence of catalytic amount of acetic acid furnishes regiospecifically an azaspiro compound. The azaspiro compound has also been
Para substituted benzaldehydes as expedient reagents for the oxidative aromatization of hydroquinoline
Majumdar, Poulomi,Pati, Anita,Behera, Rajani K.,Behera, Ajaya Kumar
, p. 703 - 712 (2013/07/05)
A Cannizzaro-type reaction of tetrahydro-5(1H)-quinolinones with para substituted benzaldehydes in the presence of a base formed the corresponding quinoline and aryl methanol rather than arylidene derivatives because of the oxidation of tetrahydroquinoline and reduction of benzaldehydes as a result of unprecedented hydride transfer from tetrahydroquinoline to arylaldehydes. The reaction proceeds best with the participation of substituents with +M effect in substrate molecule.
