99425-55-5

Basic information

• Product Name: Oxazole, 2-[3,4-dimethoxy-2-(1-methylethyl)phenyl]-4,5-dihydro-4,4-dimethyl-
• CAS NO: 99425-55-5
• Molecular Formula: C16H23NO3
• Molecular Weight: 277.364
• Mol File: 99425-55-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Oxazole, 2-[3,4-dimethoxy-2-(1-methylethyl)phenyl]-4,5-dihydro-4,4-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 2-[3,4-dimethoxy-2-(1-methylethyl)phenyl]-4,5-dihydro-4,4-dimethyl-(99425-55-5)
• EPA Substance Registry System: Oxazole, 2-[3,4-dimethoxy-2-(1-methylethyl)phenyl]-4,5-dihydro-4,4-dimethyl-(99425-55-5)

Safety Data

• Hazardous Substances Data: 99425-55-5(Hazardous Substances Data)

Upstream product

• 7169-07-5 3,4,5-(trimethoxy)benzoyl chloride 
• 573-11-5 2,3,4-Trimethoxy-benzoic acid 
• 1068-55-9 isopropylmagnesium chloride 
• 85010-19-1 4,4-dimethyl-2-(2,3,4-trimethoxyphenyl)-4,5-oxazoline 

Downstream Products

• 194998-10-2 4,4-Dimethyl-2-(5-formyl-2-isopropyl-3,4-dimethoxyphenyl)-2-oxazoline 
• 194998-11-3 2-Isopropyl-3,4-dimethoxy-5-methoxymethylbenzaldehyde 
• 77256-02-1 2-isopropyl-3,4-dimethoxybenzaldehyde 

Relevant articles and documents

An oxazoline based approach to (S)-gossypol

(S)-Gossypol (S)-1, a yellow pigment of cottonseed, has been accessed by a total asymmetric synthesis. The sequence leading to (S)-gossypol (S)-1 was highlighted by four oxazoline mediated reactions, including coupling of ortho-(methoxy)aryloxazolines with Grignard reagents, butyllithium based ortho-lithiation of aryloxazolines, stereocontrolled Ullman couplings of bromonaphthyloxazolines, and ethoxyvinyllithium hexamethylphosphoric triamide complex based ortho-lithiation of aryloxazolines.