99460-93-2Relevant academic research and scientific papers
Preparation and properties of ryodipine, an effective antihypertensive agent
Kastron,Dubur,Shatz,Yagupolsky
, p. 668 - 672 (2007/10/02)
A novel effective antihypertensive agent, 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihydro pyridine (ryodipine, PP-1466) has been obtained. A method for ryosidine synthesis has been developed, and by products of PP-1466 synthesis have been isolated and identified. Special characteristics (IRS, UVS, NMR, MS) and chromatography data (TLC, HPLC) are cited.
